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Catalog Number:
38751
CAS Number:
9003-11-6
Kolliphor P 188
Synonym(s):
Poloxamer 188, Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
Documents
$285.00 /500G
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Product Information

Kolliphor P 188, also known as Poloxamer 188, is a versatile nonionic surfactant widely utilized in pharmaceutical and cosmetic formulations. This compound is particularly valued for its ability to enhance solubility and stability of active ingredients, making it an essential component in drug delivery systems. Its unique amphiphilic structure allows it to form micelles, which can encapsulate hydrophobic drugs, thereby improving their bioavailability. Researchers and formulators often leverage Kolliphor P 188 in the development of topical creams, gels, and emulsions, where it serves to improve texture and skin feel while ensuring effective delivery of therapeutic agents.

In addition to its applications in pharmaceuticals, Kolliphor P 188 is also employed in the food and personal care industries, where it acts as an emulsifier and stabilizer. Its biocompatibility and low toxicity make it suitable for a wide range of applications, including those involving sensitive populations. With its proven efficacy and multifunctional properties, Kolliphor P 188 stands out as a reliable choice for professionals seeking to enhance product performance and consumer satisfaction.

Synonyms
Poloxamer 188, Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
CAS Number
9003-11-6
Molecular Weight
0.0
MDL Number
MFCD00082049
PubChem ID
24751
Melting Point
53 - 56 °C
Appearance
White prill/cast solid
Conditions
Store at RT
General Information
Synonyms
Poloxamer 188, Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
CAS Number
9003-11-6
Molecular Weight
0.0
MDL Number
MFCD00082049
PubChem ID
24751
Melting Point
53 - 56 °C
Appearance
White prill/cast solid
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Kolliphor P 188 is widely utilized in research focused on:

  • Pharmaceutical Formulations: It serves as a solubilizer and emulsifier in drug formulations, enhancing the bioavailability of poorly soluble drugs, which is crucial for effective medication delivery.
  • Cosmetic Products: This compound is commonly used in skincare and cosmetic formulations due to its ability to improve texture and stability, making products more appealing and effective for consumers.
  • Food Industry: Kolliphor P 188 acts as a food additive, particularly in emulsifying and stabilizing food products, ensuring consistent quality and texture in items like sauces and dressings.
  • Biotechnology: In cell culture applications, it aids in the stabilization of proteins and enzymes, which is essential for researchers working on biopharmaceuticals and diagnostics.
  • Nanotechnology: It is used in the formulation of nanoparticles for drug delivery systems, improving the targeting and release of therapeutic agents, which is a significant advancement in medical treatments.

Citations