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Catalog Number:
41574
CAS Number:
108963-96-8
Boc-Pyr-OMe
Purity:
≥ 97% (HPLC)
Synonym(s):
(S)-Methyl-N-Boc-pyroglutamate, N-Boc-(S)-2-pyrrolidone-5-carboxylic acid methyl ester, Boc-L-pyroglutamic acid methyl ester, N-Boc-5-oxo-L-proline methyl ester
Hazmat
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$72.31 /1G
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Product Information

Boc-Pyr-OMe is a versatile chemical compound widely utilized in the field of organic synthesis, particularly in peptide and pharmaceutical research. This compound features a tert-butyl and a methoxy group, which enhance its stability and solubility, making it an ideal choice for various applications. Researchers often employ Boc-Pyr-OMe as a protecting group in peptide synthesis, allowing for selective reactions and the preservation of functional groups during complex synthetic pathways. Its unique structure facilitates the formation of pyrrolidine derivatives, which are crucial in the development of bioactive molecules and drug candidates.

In addition to its role in peptide synthesis, Boc-Pyr-OMe is also valuable in the production of chiral intermediates and can be used in the synthesis of novel compounds with potential therapeutic applications. The compound's favorable properties, such as its ease of handling and compatibility with various reaction conditions, make it a preferred choice for chemists looking to streamline their synthetic processes. Whether in academic research or industrial applications, Boc-Pyr-OMe stands out as a reliable and efficient reagent for advancing chemical innovation.

Synonyms
(S)-Methyl-N-Boc-pyroglutamate, N-Boc-(S)-2-pyrrolidone-5-carboxylic acid methyl ester, Boc-L-pyroglutamic acid methyl ester, N-Boc-5-oxo-L-proline methyl ester
CAS Number
108963-96-8
Purity
≥ 97% (HPLC)
Molecular Formula
C11H17NO5
Molecular Weight
243.26
MDL Number
MFCD06809720
PubChem ID
4175931
Melting Point
68 - 72 °C
Appearance
White to tan crystalline powder
Optical Rotation
[á]22/D = -32 ° (C = 0.5 in Chloroform)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S)-Methyl-N-Boc-pyroglutamate, N-Boc-(S)-2-pyrrolidone-5-carboxylic acid methyl ester, Boc-L-pyroglutamic acid methyl ester, N-Boc-5-oxo-L-proline methyl ester
CAS Number
108963-96-8
Purity
≥ 97% (HPLC)
Molecular Formula
C11H17NO5
Molecular Weight
243.26
MDL Number
MFCD06809720
PubChem ID
4175931
Melting Point
68 - 72 °C
Appearance
White to tan crystalline powder
Optical Rotation
[á]22/D = -32 ° (C = 0.5 in Chloroform)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-Pyr-OMe is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing chemists to selectively modify amino acids without affecting others. This is crucial for creating complex peptides used in pharmaceuticals.
  • Drug Development: Its role in drug design is significant, particularly in optimizing the pharmacokinetic properties of drug candidates. Researchers can enhance solubility and stability, leading to more effective medications.
  • Bioconjugation: Boc-Pyr-OMe is employed in bioconjugation processes, where it helps attach biomolecules to drugs or imaging agents. This application is vital in developing targeted therapies and diagnostic tools in medicine.
  • Organic Synthesis: The compound is a valuable intermediate in organic synthesis, aiding in the creation of various chemical entities. Its versatility allows chemists to explore new synthetic pathways efficiently.
  • Research in Medicinal Chemistry: It is used in medicinal chemistry research to explore new compounds with potential therapeutic effects, particularly in the development of novel antibiotics and anticancer agents.

Citations