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Calcein AM solution (4 mM in DMSO)
Calcein AM solution (4 mM in DMSO) is widely utilized in research focused on:
- Cell Viability Assays: This compound is commonly used to assess cell health and viability in various biological studies. Its ability to penetrate live cells and fluoresce upon cleavage by intracellular esterases makes it an excellent indicator of cell membrane integrity.
- Fluorescence Microscopy: Researchers employ Calcein AM in fluorescence microscopy to visualize live cells in real-time. Its bright green fluorescence allows for easy monitoring of cellular processes, enhancing the understanding of cell behavior under different conditions.
- Stem Cell Research: In stem cell studies, this solution is used to track cell differentiation and proliferation. Its non-toxic nature ensures that it does not interfere with the growth and development of stem cells, providing accurate results.
- Drug Testing: The compound is valuable in pharmacological research for evaluating the cytotoxic effects of new drugs. By measuring fluorescence intensity, researchers can determine the impact of compounds on cell survival, aiding in drug development.
- Environmental Toxicology: Calcein AM is utilized in environmental studies to assess the toxicity of pollutants on aquatic organisms. Its ability to indicate live cells helps in understanding the effects of environmental stressors on ecosystems.
General Information
Properties
Safety and Regulations
Applications
Calcein AM solution (4 mM in DMSO) is widely utilized in research focused on:
- Cell Viability Assays: This compound is commonly used to assess cell health and viability in various biological studies. Its ability to penetrate live cells and fluoresce upon cleavage by intracellular esterases makes it an excellent indicator of cell membrane integrity.
- Fluorescence Microscopy: Researchers employ Calcein AM in fluorescence microscopy to visualize live cells in real-time. Its bright green fluorescence allows for easy monitoring of cellular processes, enhancing the understanding of cell behavior under different conditions.
- Stem Cell Research: In stem cell studies, this solution is used to track cell differentiation and proliferation. Its non-toxic nature ensures that it does not interfere with the growth and development of stem cells, providing accurate results.
- Drug Testing: The compound is valuable in pharmacological research for evaluating the cytotoxic effects of new drugs. By measuring fluorescence intensity, researchers can determine the impact of compounds on cell survival, aiding in drug development.
- Environmental Toxicology: Calcein AM is utilized in environmental studies to assess the toxicity of pollutants on aquatic organisms. Its ability to indicate live cells helps in understanding the effects of environmental stressors on ecosystems.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
*Catalog Number
*Lot Number
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.