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Catalog Number:
42382
CAS Number:
120791-76-6
Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-threonine tert-butyl ester
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Nα-Fmoc-L-threonine tert-butyl ester, Fmoc-Thr-OtBu
Documents
$184.28 /1G
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Product Information

Na-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-threonine tert-butyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective group that enhances the stability and solubility of L-threonine, making it an ideal choice for researchers looking to develop complex peptides and proteins. Its unique structure allows for selective reactions, facilitating the synthesis of various bioactive molecules. The tert-butyl ester group not only improves the compound's handling properties but also aids in the purification processes, which is crucial in both academic and industrial settings.

In addition to its applications in peptide chemistry, this compound is recognized for its potential in drug development, particularly in the design of therapeutics that target specific biological pathways. Its ability to serve as a building block in the synthesis of more complex molecules positions it as a valuable asset in medicinal chemistry. Researchers and industry professionals can leverage this compound to streamline their workflows and enhance the efficiency of their synthesis processes, ultimately leading to faster development times for new drugs and therapies.

Synonyms
Nα-Fmoc-L-threonine tert-butyl ester, Fmoc-Thr-OtBu
CAS Number
120791-76-6
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C23H27NO5
Molecular Weight
397.47
MDL Number
MFCD08276378
PubChem ID
14410183
Melting Point
100 °C
Appearance
White solid
Optical Rotation
α20D = -11 to -4 ° (C=1 in CHCl3)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Nα-Fmoc-L-threonine tert-butyl ester, Fmoc-Thr-OtBu
CAS Number
120791-76-6
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C23H27NO5
Molecular Weight
397.47
MDL Number
MFCD08276378
PubChem ID
14410183
Melting Point
100 °C
Appearance
White solid
Optical Rotation
α20D = -11 to -4 ° (C=1 in CHCl3)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-threonine tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without unwanted side reactions. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, it plays a crucial role in the development of new drugs, particularly in modifying amino acids to enhance bioavailability and efficacy.
  • Biotechnology: The compound is used in the production of recombinant proteins, aiding in the development of therapeutic proteins by providing a stable structure during the synthesis process.
  • Analytical Chemistry: It is utilized in analytical methods for the detection and quantification of amino acids, improving the accuracy of results in various assays.
  • Material Science: The compound can be incorporated into polymer systems to create materials with specific properties, such as improved mechanical strength or biocompatibility, which are essential in medical applications.

Citations