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Catalog Number:
47021
Fmoc-D-Phe(4-COOtBu)-OH
Purity:
≥ 99.5% (Chiral HPLC)
Documents
$210.00 /100MG
Pack Size Availability Price
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Product Information

Fmoc-D-Phe(4-COOtBu)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. The presence of the tert-butyl ester (tBu) at the 4-position enhances its stability and solubility, making it an ideal choice for researchers working in organic chemistry and biochemistry.

This compound is particularly valuable in the pharmaceutical industry for the development of peptide-based therapeutics, where precise control over amino acid sequences is essential. Its unique properties allow for efficient coupling reactions and facilitate the synthesis of complex peptides with high purity. Researchers can leverage Fmoc-D-Phe(4-COOtBu)-OH to streamline their workflows, reduce reaction times, and improve yields in peptide synthesis, ultimately leading to more effective drug candidates.

Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C29H29NO6
Molecular Weight
487.54
Appearance
White powder
Optical Rotation
[ॅ]D20 = 25 +/- 1 ° (C=1 in DMF)
Conditions
Store at RT
General Information
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C29H29NO6
Molecular Weight
487.54
Appearance
White powder
Optical Rotation
[ॅ]D20 = 25 +/- 1 ° (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-Phe(4-COOtBu)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective Fmoc group allows for selective deprotection, facilitating the assembly of complex peptide chains.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, which can target specific biological pathways. This specificity can lead to more effective treatments with fewer side effects compared to traditional small molecule drugs.
  • Bioconjugation: The compound can be employed in bioconjugation processes, where it helps attach peptides to other biomolecules, such as antibodies or enzymes, enhancing their functionality in therapeutic applications.
  • Research in Cancer Therapeutics: Researchers utilize this compound in developing targeted therapies for cancer, leveraging its ability to form peptides that can bind to cancer cells, potentially improving treatment efficacy.
  • Protein Engineering: It plays a role in protein engineering, allowing scientists to modify proteins for enhanced stability or activity, thus advancing research in biotechnology and synthetic biology.

Citations