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Catalog Number:
47441
CAS Number:
102417-94-7
Dansylamino-PITC
Purity:
≥ 98% (HPLC)
Synonym(s):
4-(Dansylamino)phenyl isothiocyanate, 4-[[5-(Dimethylamino)-1-naphthylsulfonyl]amino]phenyl isothiocyanate
Documents
$152.40 /100MG
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Product Information

Dansylamino-PITC is a versatile compound widely utilized in biochemical research, particularly in the field of protein labeling and analysis. This compound features a unique dansyl group that enhances fluorescence, making it an excellent choice for tracking and visualizing proteins in various biological assays. Its isothiocyanate functionality allows for efficient conjugation to amine-containing biomolecules, facilitating the development of highly specific probes for studying protein interactions and dynamics. Researchers appreciate Dansylamino-PITC for its stability and strong fluorescent properties, which contribute to clearer imaging and more reliable results in applications such as flow cytometry and fluorescence microscopy.

In addition to its role in protein studies, Dansylamino-PITC is also employed in the synthesis of peptide-based drugs and in the development of diagnostic assays. Its ability to form stable conjugates with proteins and peptides makes it invaluable for creating targeted therapies and diagnostic tools. The compound's unique characteristics, including its high sensitivity and specificity, set it apart from similar labeling agents, making it a preferred choice for professionals in the life sciences and pharmaceutical industries.

Synonyms
4-(Dansylamino)phenyl isothiocyanate, 4-[[5-(Dimethylamino)-1-naphthylsulfonyl]amino]phenyl isothiocyanate
CAS Number
102417-94-7
Purity
≥ 98% (HPLC)
Molecular Formula
C19H17N3O2S2
Molecular Weight
383.48
MDL Number
MFCD00077739
PubChem ID
128100
Melting Point
127 - 131 °C
Appearance
Pale yellow to amber to green powder
Optical Rotation
[a]20/D = 38 - 45 ° (C=0.2 in THF)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
4-(Dansylamino)phenyl isothiocyanate, 4-[[5-(Dimethylamino)-1-naphthylsulfonyl]amino]phenyl isothiocyanate
CAS Number
102417-94-7
Purity
≥ 98% (HPLC)
Molecular Formula
C19H17N3O2S2
Molecular Weight
383.48
MDL Number
MFCD00077739
PubChem ID
128100
Melting Point
127 - 131 °C
Appearance
Pale yellow to amber to green powder
Optical Rotation
[a]20/D = 38 - 45 ° (C=0.2 in THF)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Dansylamino-PITC is widely utilized in research focused on:

  • Protein Labeling: This compound is commonly used to label proteins for fluorescence studies, allowing researchers to track protein interactions and dynamics in live cells.
  • Peptide Synthesis: It serves as a valuable reagent in peptide synthesis, enhancing the efficiency of coupling reactions and improving yield in the production of bioactive peptides.
  • Diagnostics: Dansylamino-PITC is employed in diagnostic applications, particularly in the detection of specific biomolecules, aiding in disease diagnosis and monitoring.
  • Drug Development: In pharmaceutical research, it is utilized to study drug interactions and mechanisms, providing insights that can lead to the development of more effective therapeutics.
  • Environmental Monitoring: This chemical is also applied in environmental science for the detection of pollutants, helping to assess water quality and the presence of hazardous substances.

Citations