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Catalog Number:
43413
CAS Number:
130250-54-3
Ethyl 1-(tert-butoxycarbonyl)-3-piperidinecarboxylate
Purity:
≥ 98% (GC)
Synonym(s):
Ethyl 1-Boc-3-piperidinecarboxylate, 1-Boc-nipecotic acid ethyl ester, Ethyl 1-boc-nipecotate, 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid ethyl ester
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Product Information

Ethyl 1-(tert-butoxycarbonyl)-3-piperidinecarboxylate is a versatile compound widely utilized in the synthesis of various pharmaceuticals and agrochemicals. This compound, often referred to as Ethyl Boc-piperidine-3-carboxylate, features a tert-butoxycarbonyl (Boc) protecting group that enhances its stability and reactivity in organic synthesis. Its unique structure allows for selective reactions, making it an essential intermediate in the development of complex molecules. Researchers and industry professionals appreciate its role in the synthesis of piperidine derivatives, which are crucial in the production of analgesics, antidepressants, and other therapeutic agents.

In addition to its pharmaceutical applications, Ethyl 1-(tert-butoxycarbonyl)-3-piperidinecarboxylate is also valuable in the field of agrochemicals, where it serves as a building block for the development of new pesticides and herbicides. Its favorable properties, such as solubility and stability, make it an attractive choice for formulation chemists. By incorporating this compound into their research and development processes, professionals can streamline their workflows and enhance the efficiency of their synthetic routes, ultimately leading to innovative solutions in both healthcare and agriculture.

Synonyms
Ethyl 1-Boc-3-piperidinecarboxylate, 1-Boc-nipecotic acid ethyl ester, Ethyl 1-boc-nipecotate, 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid ethyl ester
CAS Number
130250-54-3
Purity
≥ 98% (GC)
Molecular Formula
C13H23NO4
Molecular Weight
257.33
MDL Number
MFCD04116274
PubChem ID
357727
Melting Point
34 - 38 °C
Appearance
White to yellow to orange powder or lump
Boiling Point
93 °C/0.027 mmHg
Conditions
Store at RT
General Information
Synonyms
Ethyl 1-Boc-3-piperidinecarboxylate, 1-Boc-nipecotic acid ethyl ester, Ethyl 1-boc-nipecotate, 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid ethyl ester
CAS Number
130250-54-3
Purity
≥ 98% (GC)
Molecular Formula
C13H23NO4
Molecular Weight
257.33
MDL Number
MFCD04116274
PubChem ID
357727
Melting Point
34 - 38 °C
Appearance
White to yellow to orange powder or lump
Boiling Point
93 °C/0.027 mmHg
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ethyl 1-(tert-butoxycarbonyl)-3-piperidinecarboxylate is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly in the development of piperidine-based drugs, which are known for their efficacy in treating neurological disorders.
  • Peptide Chemistry: It is used in the protection of amine groups during peptide synthesis, allowing for the selective modification of other functional groups without affecting the piperidine structure.
  • Organic Synthesis: The compound acts as a versatile building block in organic chemistry, facilitating the creation of complex molecules through various reactions, such as nucleophilic substitutions.
  • Research in Drug Development: Its unique structure makes it valuable in medicinal chemistry research, where it aids in the design and optimization of new drug candidates with improved pharmacological profiles.
  • Material Science: This chemical is also explored in the development of new materials, particularly in the creation of polymers that require specific functional groups for enhanced properties.

Citations