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Catalog Number:
45292
CAS Number:
205865-67-4
Ethyl 2,2-difluoro-2-(trimethylsilyl)acetate
Purity:
≥ 97% (GC)
Synonym(s):
2,2-Difluoro-2-(trimethylsilyl)acetic acid ethyl ester
Hazmat
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$139.90 /1G
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Product Information

Ethyl 2,2-difluoro-2-(trimethylsilyl)acetate is a versatile chemical compound that finds significant applications in organic synthesis and pharmaceutical development. This compound is characterized by its unique difluoroacetate structure, which enhances its reactivity and stability, making it an ideal candidate for various chemical transformations. Researchers and industry professionals utilize this compound in the synthesis of fluorinated compounds, which are crucial in the development of agrochemicals and pharmaceuticals. Its trimethylsilyl group also provides enhanced solubility and protection of functional groups during synthetic processes, thereby streamlining the overall synthesis workflow.

In addition to its synthetic utility, Ethyl 2,2-difluoro-2-(trimethylsilyl)acetate serves as a valuable reagent in the preparation of complex molecules, including those used in medicinal chemistry. Its ability to introduce fluorine atoms into organic molecules can significantly alter their biological activity, making it a key player in drug discovery and development. The compound's unique properties not only facilitate the creation of novel compounds but also enhance the efficiency of existing synthetic routes, providing researchers with a powerful tool for advancing their projects.

Synonyms
2,2-Difluoro-2-(trimethylsilyl)acetic acid ethyl ester
CAS Number
205865-67-4
Purity
≥ 97% (GC)
Molecular Formula
C7H14F2O2Si
Molecular Weight
196.27
MDL Number
MFCD04973092
PubChem ID
2758940
Density
1.03
Appearance
Colorless to light yellow clear liquid to cloudy liquid
Boiling Point
55 °C/20 mmHg
Refractive Index
n20D 1.39
Conditions
Store at RT
General Information
Synonyms
2,2-Difluoro-2-(trimethylsilyl)acetic acid ethyl ester
CAS Number
205865-67-4
Purity
≥ 97% (GC)
Molecular Formula
C7H14F2O2Si
Molecular Weight
196.27
MDL Number
MFCD04973092
PubChem ID
2758940
Density
1.03
Appearance
Colorless to light yellow clear liquid to cloudy liquid
Boiling Point
55 °C/20 mmHg
Refractive Index
n20D 1.39
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ethyl 2,2-difluoro-2-(trimethylsilyl)acetate is widely utilized in research focused on:

  • Synthetic Chemistry: This compound serves as a versatile building block in the synthesis of various fluorinated compounds, which are important in pharmaceuticals and agrochemicals.
  • Drug Development: Its unique fluorinated structure enhances the biological activity and stability of drug candidates, making it valuable in medicinal chemistry.
  • Material Science: Used in the development of advanced materials, it contributes to the creation of coatings and polymers with improved chemical resistance and durability.
  • Analytical Chemistry: This compound can be employed as a derivatizing agent in mass spectrometry, aiding in the analysis of complex mixtures by enhancing detection sensitivity.
  • Fluorine Chemistry: It plays a crucial role in the study of fluor

Citations