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Catalog Number:
37333
CAS Number:
25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
Purity:
≥ 99% (GC)
Synonym(s):
BSTFA
Hazmat
Documents
$25.00 /25G
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Product Information

N,O-Bis(trimethylsilyl)trifluoroacetamide is a highly versatile reagent widely utilized in organic synthesis and analytical chemistry. This compound serves as an effective derivatizing agent, particularly in the preparation of volatile derivatives for gas chromatography (GC) analysis. Its unique trifluoroacetamide moiety enhances the volatility and thermal stability of various analytes, making it an essential tool for researchers in fields such as environmental analysis, pharmaceuticals, and food safety. The presence of trimethylsilyl groups further improves the solubility and reactivity of the compound, allowing for efficient derivatization of polar functional groups.

In addition to its applications in GC, N,O-Bis(trimethylsilyl)trifluoroacetamide is also beneficial in mass spectrometry (MS) for the analysis of complex mixtures. Its ability to form stable derivatives with amines, alcohols, and carboxylic acids makes it invaluable for characterizing a wide range of organic compounds. Researchers and industry professionals can leverage this compound to enhance the sensitivity and specificity of their analytical methods, ultimately leading to more accurate and reliable results.

Synonyms
BSTFA
CAS Number
25561-30-2
Purity
≥ 99% (GC)
Molecular Formula
C8H18F3NOSi2
Molecular Weight
257.4
MDL Number
MFCD00008269
PubChem ID
94358
Melting Point
-10 °C (Lit.)
Density
0.97
Appearance
Colorless transparent liquid
Boiling Point
45 - 50 °C / 14 mmHg
Refractive Index
n20/D 1.384
Conditions
Store at 0 - 8 °C
General Information
Synonyms
BSTFA
CAS Number
25561-30-2
Purity
≥ 99% (GC)
Molecular Formula
C8H18F3NOSi2
Molecular Weight
257.4
MDL Number
MFCD00008269
PubChem ID
94358
Melting Point
-10 °C (Lit.)
Density
0.97
Appearance
Colorless transparent liquid
Boiling Point
45 - 50 °C / 14 mmHg
Refractive Index
n20/D 1.384
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N,O-Bis(trimethylsilyl)trifluoroacetamide is widely utilized in research focused on:

  • Gas Chromatography (GC): This compound serves as a derivatizing agent, enhancing the volatility and stability of polar compounds, making them easier to analyze in GC applications.
  • Mass Spectrometry (MS): It improves the ionization efficiency of various analytes, allowing for more sensitive detection in mass spectrometric analyses, which is crucial in fields like environmental testing and pharmaceuticals.
  • Organic Synthesis: Used in the synthesis of various organic compounds, it helps in the formation of stable derivatives, facilitating the identification and quantification of target molecules.
  • Proteomics: In biological research, it aids in the derivatization of amino acids and peptides, enhancing their detectability and separation in complex biological samples.
  • Material Science: This chemical is employed in the modification of polymers and materials, improving their thermal and chemical resistance, which is beneficial in the development of advanced materials.

Citations