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Catalog Number:
31224
CAS Number:
206190-14-9
Pentafluorphenol-tetramethyluronium hexafluorophosphate
Purity:
≥ 99% (HPLC)
Synonym(s):
PFTU, (Dimethylamino)dimethyl(2,3,4,5,6-pentafluorophenoxy)methanaminium hexafluorophosphate
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$36.65 /1G
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Product Information

Pentafluorphenol-tetramethyluronium hexafluorophosphate is a highly specialized reagent known for its exceptional utility in organic synthesis and pharmaceutical research. This compound serves as a powerful coupling agent, facilitating the formation of amide bonds and other critical linkages in complex molecular architectures. Its unique structure, featuring a pentafluorophenol moiety, enhances its reactivity and selectivity, making it an invaluable tool for chemists aiming to streamline synthetic pathways. Researchers appreciate its ability to operate under mild conditions, which minimizes the risk of side reactions and degradation of sensitive substrates.

In addition to its role in organic synthesis, Pentafluorphenol-tetramethyluronium hexafluorophosphate is also utilized in the development of advanced materials and in the field of medicinal chemistry. Its high solubility in organic solvents and stability under various conditions allow for versatile applications, including peptide synthesis and the preparation of complex heterocycles. This compound stands out among similar reagents due to its efficiency and the purity of the products it yields, making it a preferred choice for professionals seeking reliable and effective solutions in their research and development endeavors.

Synonyms
PFTU, (Dimethylamino)dimethyl(2,3,4,5,6-pentafluorophenoxy)methanaminium hexafluorophosphate
CAS Number
206190-14-9
Purity
≥ 99% (HPLC)
Molecular Formula
C11H12F5N2O·PF6
Molecular Weight
428.18
MDL Number
MFCD04973269
PubChem ID
15840204
Melting Point
175 - 185 °C
Appearance
Off-white to white crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
PFTU, (Dimethylamino)dimethyl(2,3,4,5,6-pentafluorophenoxy)methanaminium hexafluorophosphate
CAS Number
206190-14-9
Purity
≥ 99% (HPLC)
Molecular Formula
C11H12F5N2O·PF6
Molecular Weight
428.18
MDL Number
MFCD04973269
PubChem ID
15840204
Melting Point
175 - 185 °C
Appearance
Off-white to white crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pentafluorphenol-tetramethyluronium hexafluorophosphate is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an efficient coupling reagent in the synthesis of peptides, enhancing yield and purity compared to traditional methods.
  • Pharmaceutical Development: It is employed in the formulation of active pharmaceutical ingredients (APIs), particularly in optimizing solubility and stability of drug compounds.
  • Organic Synthesis: Researchers use it for various organic transformations, benefiting from its ability to activate carboxylic acids and facilitate ester formation.
  • Fluorinated Compounds Production: The unique fluorinated structure allows for the creation of novel fluorinated materials, which are valuable in advanced materials science and electronics.
  • Analytical Chemistry: It is utilized in analytical methods for detecting and quantifying specific compounds, improving sensitivity and selectivity in various assays.

Citations