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Catalog Number:
02601
CAS Number:
136030-33-6
Fmoc-(3S-)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Purity:
≥ 99% (Chiral HPLC)
Synonym(s):
Fmoc-L-Tic-OH, Fmoc-Tic-OH
Documents
$20.00 /1G
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Product Information

Fmoc-(3S-)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is a versatile compound widely utilized in the field of organic synthesis and peptide chemistry. This compound serves as a crucial building block in the development of peptide-based therapeutics and drug discovery, particularly due to its ability to facilitate the introduction of functional groups in a controlled manner. Its unique Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection, making it an essential tool for chemists aiming to synthesize complex peptide sequences with precision.

In addition to its applications in peptide synthesis, this compound has shown promise in medicinal chemistry, where it can be utilized to create novel isoquinoline derivatives with potential biological activity. Researchers appreciate its stability and ease of handling, which enhances its appeal in laboratory settings. The compound's specific stereochemistry also contributes to its effectiveness in various reactions, providing an edge over similar compounds in terms of yield and selectivity.

Synonyms
Fmoc-L-Tic-OH, Fmoc-Tic-OH
CAS Number
136030-33-6
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C25H21NO4
Molecular Weight
399.4
MDL Number
MFCD00144368
PubChem ID
6957976
Melting Point
150 - 170 °C
Appearance
White powder
Optical Rotation
[a]D20 = + 26 ±3 °(C=1 in MeOH)
Conditions
Store at 0 - 8 °
General Information
Synonyms
Fmoc-L-Tic-OH, Fmoc-Tic-OH
CAS Number
136030-33-6
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C25H21NO4
Molecular Weight
399.4
MDL Number
MFCD00144368
PubChem ID
6957976
Melting Point
150 - 170 °C
Appearance
White powder
Optical Rotation
[a]D20 = + 26 ±3 °(C=1 in MeOH)
Conditions
Store at 0 - 8 °
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(3S-)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting the rest of the molecule. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its structural properties make it valuable in designing new drugs, particularly in creating compounds that target specific biological pathways, enhancing efficacy and reducing side effects.
  • Organic Synthesis: The compound is used in various organic synthesis applications, providing a versatile building block for creating other complex molecules in chemical research and development.
  • Biotechnology: In biotechnology, it plays a role in the development of bioconjugates, which are important for targeted drug delivery systems, improving therapeutic outcomes.
  • Research in Neuroscience: Its derivatives are studied for their potential effects on neurological pathways, making it a candidate for research into treatments for neurodegenerative diseases.

Citations