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Catalog Number:
15635
CAS Number:
511272-31-4
Fmoc-(R)-3-amino-3-(2-methoxyphenyl)propionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-β-Phe(2-OMe)-OH, (R-Fmoc-2-methoxy-β-phenylalanine
Documents
$72.31 /100MG
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Product Information

Fmoc-(R)-3-amino-3-(2-methoxyphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique structure, characterized by the presence of a methoxyphenyl group, enhances its reactivity and compatibility with various coupling reagents, making it an ideal choice for researchers looking to develop complex peptide sequences.

In addition to its role in peptide synthesis, Fmoc-(R)-3-amino-3-(2-methoxyphenyl)propionic acid has potential applications in drug development, particularly in the design of bioactive compounds. Its ability to facilitate the introduction of specific amino acid residues allows for the creation of peptides with tailored biological activities. This compound is particularly beneficial for researchers focused on developing therapeutics targeting specific pathways, as it provides a reliable method for incorporating functionalized amino acids into peptide chains. With its robust performance and adaptability, this compound stands out as a valuable asset in the toolkit of chemists and pharmaceutical developers.

Synonyms
Fmoc-D-β-Phe(2-OMe)-OH, (R-Fmoc-2-methoxy-β-phenylalanine
CAS Number
511272-31-4
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.46
MDL Number
MFCD03428012
PubChem ID
22831634
Melting Point
134-140ºC
Appearance
White powder
Optical Rotation
[a]D25 = +18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-Phe(2-OMe)-OH, (R-Fmoc-2-methoxy-β-phenylalanine
CAS Number
511272-31-4
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.46
MDL Number
MFCD03428012
PubChem ID
22831634
Melting Point
134-140ºC
Appearance
White powder
Optical Rotation
[a]D25 = +18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(2-methoxyphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It is used in the pharmaceutical industry for developing new drugs, especially those targeting specific receptors, due to its ability to enhance the stability and bioavailability of peptide-based therapeutics.
  • Bioconjugation: The chemical is valuable in bioconjugation processes, where it helps attach peptides to other molecules, improving the efficacy of drug delivery systems and diagnostic agents.
  • Research in Neuroscience: Its applications extend to neuroscience research, where it aids in studying neuropeptides that play crucial roles in brain function and behavior, helping to unravel complex neurological pathways.
  • Custom Synthesis Services: Many contract research organizations utilize this compound for custom synthesis projects, providing tailored solutions for clients needing specific peptide sequences for research or therapeutic applications.

Citations