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Catalog Number:
15657
CAS Number:
511272-35-8
Fmoc-(R)-3-amino-3-(3-hydroxyphenyl)propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-β-Phe(3-OH)-OH, Fmo-D-β-m-Tyr-OH
Documents
$180.00 /1G
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Product Information

Fmoc-(R)-3-amino-3-(3-hydroxyphenyl)propionic acid is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for the introduction of a 3-hydroxyphenyl side chain, enhancing the compound's potential in developing bioactive peptides and drug candidates. Researchers appreciate its stability under various conditions, making it an ideal choice for solid-phase peptide synthesis and other synthetic methodologies.

In addition to its role in peptide synthesis, Fmoc-(R)-3-amino-3-(3-hydroxyphenyl)propionic acid has shown promise in the development of therapeutic agents targeting various biological pathways. Its ability to facilitate the incorporation of hydrophobic and polar residues into peptides opens avenues for creating more effective and selective drugs. This compound is particularly relevant for researchers focused on medicinal chemistry and drug design, as it can lead to the development of novel therapeutic strategies with enhanced efficacy and reduced side effects.

Synonyms
Fmoc-D-β-Phe(3-OH)-OH, Fmo-D-β-m-Tyr-OH
CAS Number
511272-35-8
Purity
≥ 98% (HPLC)
Molecular Formula
C24H21NO5
Molecular Weight
403.43
MDL Number
MFCD03428016
PubChem ID
24902255
Melting Point
158 - 160 °C
Appearance
White powder
Optical Rotation
[a]D25 = +29 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-Phe(3-OH)-OH, Fmo-D-β-m-Tyr-OH
CAS Number
511272-35-8
Purity
≥ 98% (HPLC)
Molecular Formula
C24H21NO5
Molecular Weight
403.43
MDL Number
MFCD03428016
PubChem ID
24902255
Melting Point
158 - 160 °C
Appearance
White powder
Optical Rotation
[a]D25 = +29 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(3-hydroxyphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing novel drugs, especially those targeting neurological disorders, due to its ability to mimic natural amino acids.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems.
  • Research in Neuroscience: Its structural properties make it valuable in neuroscience research, particularly in studying receptor interactions and signaling pathways related to neurotransmitters.
  • Functional Materials: This chemical is also explored in the development of functional materials, such as hydrogels and nanomaterials, which have applications in tissue engineering and regenerative medicine.

Citations