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Catalog Number:
04565
CAS Number:
21027-72-5
Gly-Phe-pNA·HCl
Purity:
≥ 99% (HPLC)
Synonym(s):
Cathepsin C substrate, hydrochloride, Glycyl-L-phenylalanine p-nitroanilide hydrochloride
Documents
$120.88 /100MG
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Product Information

Gly-Phe-pNA·HCl is a potent synthetic compound widely utilized in biochemical research, particularly in the study of enzyme kinetics and protease activity. This compound serves as a substrate for various proteolytic enzymes, allowing researchers to investigate enzyme mechanisms and inhibition. Its unique structure, featuring a phenylalanine and a glycine moiety, enhances its specificity and sensitivity in assays, making it an invaluable tool in drug discovery and development.

In addition to its applications in enzymology, Gly-Phe-pNA·HCl is also employed in the synthesis of peptide-based therapeutics, where its ability to mimic natural substrates can facilitate the design of more effective drugs. The hydrochloride salt form ensures high solubility and stability, which are critical for laboratory experiments. With its versatile applications and reliable performance, Gly-Phe-pNA·HCl stands out as a preferred choice for researchers aiming to advance their studies in biochemistry and pharmacology.

Synonyms
Cathepsin C substrate, hydrochloride, Glycyl-L-phenylalanine p-nitroanilide hydrochloride
CAS Number
21027-72-5
Purity
≥ 99% (HPLC)
Molecular Formula
C17H18N4O4·HCl
Molecular Weight
378.82
MDL Number
MFCD00151682
PubChem ID
3508173
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Cathepsin C substrate, hydrochloride, Glycyl-L-phenylalanine p-nitroanilide hydrochloride
CAS Number
21027-72-5
Purity
≥ 99% (HPLC)
Molecular Formula
C17H18N4O4·HCl
Molecular Weight
378.82
MDL Number
MFCD00151682
PubChem ID
3508173
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Gly-Phe-pNA·HCl is widely utilized in research focused on:

  • Enzyme Activity Assays: This compound serves as a substrate in assays to measure the activity of specific proteolytic enzymes, helping researchers understand enzyme kinetics and inhibition.
  • Drug Development: It is used in the pharmaceutical industry for screening potential drug candidates that target proteases, which are crucial in various diseases, including cancer and viral infections.
  • Biochemical Research: Gly-Phe-pNA·HCl is employed in studies investigating protein interactions and modifications, providing insights into cellular processes and signaling pathways.
  • Diagnostic Applications: This compound can be utilized in developing diagnostic tests for diseases that involve protease activity, offering a reliable method for early detection and monitoring.
  • Educational Purposes: It is often used in academic laboratories for teaching purposes, allowing students to explore enzyme-substrate interactions and the principles of biochemistry in a hands-on manner.

Citations