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Catalog Number:
04790
CAS Number:
170642-27-0
Fmoc-D-α-aminobutyric acid
Purity:
≥ 99%
Synonym(s):
Fmoc-D-Abu-OH, Fmoc-D-2-aminobutanoic acid
Documents
$18.53 /1G
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Product Information

Fmoc-D-a-aminobutyric acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers aiming to create complex peptide sequences with high purity and yield.

In addition to its application in peptide synthesis, Fmoc-D-a-aminobutyric acid is also employed in the development of pharmaceuticals and biologically active compounds. Its ability to enhance solubility and stability in various formulations makes it a valuable asset in medicinal chemistry. Researchers appreciate its compatibility with various coupling reagents and its ease of removal under mild conditions, which streamlines the synthesis process. This compound not only facilitates the creation of novel peptides but also supports advancements in therapeutic research, making it a crucial component in the toolkit of chemists and biochemists alike.

Synonyms
Fmoc-D-Abu-OH, Fmoc-D-2-aminobutanoic acid
CAS Number
170642-27-0
Purity
≥ 99%
Molecular Formula
C19H19NO4
Molecular Weight
325.4
MDL Number
MFCD00270336
PubChem ID
4248192
Melting Point
120-127 °C
Optical Rotation
[a]D20 = +19 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Abu-OH, Fmoc-D-2-aminobutanoic acid
CAS Number
170642-27-0
Purity
≥ 99%
Molecular Formula
C19H19NO4
Molecular Weight
325.4
MDL Number
MFCD00270336
PubChem ID
4248192
Melting Point
120-127 °C
Optical Rotation
[a]D20 = +19 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-a-aminobutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its ability to enhance the stability and bioavailability of peptide-based drugs makes it valuable in pharmaceutical formulations, particularly in the development of targeted therapies.
  • Bioconjugation: Fmoc-D-a-aminobutyric acid is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutics.
  • Research in Neuroscience: The compound is instrumental in studying neuropeptides, contributing to insights into neurological disorders and potential treatments.
  • Custom Synthesis: It is often employed in custom synthesis projects for researchers needing specific amino acid derivatives, providing flexibility and precision in experimental designs.

Citations