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Catalog Number:
30486
CAS Number:
182618-30-0
Clorhidrato de éster terc-butílico del ácido Na-Fmoc-L-2,3-diaminopropiónico
Purity:
99 - 101% (Ensayo por titulación)
Synonym(s):
Fmoc-L-Dap-OtBu·HCl
Documents
$81.26 /250 mg
Tamaño
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Product Information

Na-Fmoc-L-2,3-diaminopropionic acid tert-butyl ester hydrochloride is a versatile compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides stability and ease of handling during the synthesis of peptides. Its unique structure allows for selective deprotection, making it an essential building block for researchers in the fields of medicinal chemistry and biochemistry. The tert-butyl ester group enhances solubility, facilitating its use in various organic reactions and applications.

This compound is particularly valuable in the synthesis of complex peptides and proteins, enabling the incorporation of specific amino acids into sequences with precision. Its application extends to the development of therapeutic peptides, where the ability to control the synthesis process is crucial. Researchers appreciate its compatibility with standard coupling reagents and its effectiveness in solid-phase peptide synthesis. With its robust performance and reliability, Na-Fmoc-L-2,3-diaminopropionic acid tert-butyl ester hydrochloride stands out as a preferred choice for professionals seeking high-quality reagents for their research and development projects.

Synonyms
Fmoc-L-Dap-OtBu·HCl
CAS Number
182618-30-0
Purity
99 - 101% (Ensayo por titulación)
Molecular Formula
C22H27ClN2O4
Molecular Weight
418.9
MDL Number
MFCD21363165
PubChem ID
69490749
Melting Point
161 - 162 °C (descenso)
Appearance
Polvo cristalino blanco
Optical Rotation
[a] D 20 = -32 ± 2 º (C=1 en MeOH)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-L-Dap-OtBu·HCl
CAS Number
182618-30-0
Purity
99 - 101% (Ensayo por titulación)
Molecular Formula
C22H27ClN2O4
Molecular Weight
418.9
MDL Number
MFCD21363165
PubChem ID
69490749
Melting Point
161 - 162 °C (descenso)
Appearance
Polvo cristalino blanco
Optical Rotation
[a] D 20 = -32 ± 2 º (C=1 en MeOH)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-L-2,3-diaminopropionic acid tert-butyl ester hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex and biologically active peptides.
  • Drug Development: It is used in the pharmaceutical industry to develop new drugs, especially those targeting specific biological pathways, due to its ability to form stable peptide bonds.
  • Bioconjugation: The chemical is employed in bioconjugation processes, where it helps attach biomolecules to other molecules, enhancing the efficacy of therapeutic agents.
  • Research in Neuroscience: Its derivatives are explored in neuroscience for the development of neuropeptides, contributing to the understanding of neurological functions and potential treatments for disorders.
  • Custom Synthesis: Researchers utilize it for custom synthesis of modified amino acids, which can be tailored for specific research needs, offering flexibility in experimental design.

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