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Catalog Number:
37709
CAS Number:
103766-25-2
Gimeracilo
Purity:
≥ 98% (ensayo por titulación, HPLC)
Synonym(s):
5-Cloro-2,4-dihidroxipiridina, 5-Cloro-4-hidroxi-2(1 H )-piridinona
Documents
$91.74 /1G
Tamaño
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Product Information

Gimeracil is a potent compound recognized for its role as a key intermediate in the synthesis of various pharmaceuticals, particularly in the field of oncology. This compound, also known as 5-chloro-4-hydroxy-1H-pyridin-2-one, exhibits unique properties that make it invaluable in drug development processes. Gimeracil functions primarily as a dihydropyrimidine dehydrogenase inhibitor, which enhances the efficacy of certain chemotherapeutic agents by preventing their degradation. This characteristic is particularly beneficial in combination therapies, allowing for improved therapeutic outcomes in cancer treatment.

In addition to its applications in cancer therapy, Gimeracil has shown promise in enhancing the bioavailability of other drugs, making it a versatile tool in pharmaceutical formulations. Researchers and industry professionals can leverage Gimeracil's properties to optimize drug efficacy and patient outcomes. Its ability to stabilize active pharmaceutical ingredients under various conditions further underscores its relevance in the pharmaceutical industry, making it an essential compound for those focused on innovative drug solutions.

Synonyms
5-Cloro-2,4-dihidroxipiridina, 5-Cloro-4-hidroxi-2(1 H )-piridinona
CAS Number
103766-25-2
Purity
≥ 98% (ensayo por titulación, HPLC)
Molecular Formula
C5H4ClNO2
Molecular Weight
145.54
MDL Number
MFCD08458352
PubChem ID
54679224
Melting Point
274 °C (descenso)
Appearance
Polvo blanco a casi blanco a cristal.
Conditions
Conservar entre 2 y 8 °C.
General Information
Synonyms
5-Cloro-2,4-dihidroxipiridina, 5-Cloro-4-hidroxi-2(1 H )-piridinona
CAS Number
103766-25-2
Purity
≥ 98% (ensayo por titulación, HPLC)
Molecular Formula
C5H4ClNO2
Molecular Weight
145.54
MDL Number
MFCD08458352
PubChem ID
54679224
Melting Point
274 °C (descenso)
Appearance
Polvo blanco a casi blanco a cristal.
Conditions
Conservar entre 2 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Gimeracil is widely utilized in research focused on:

  • Oncology: It acts as a potent enhancer of chemotherapy, particularly in combination with fluorouracil, improving treatment outcomes for cancer patients.
  • Pharmaceutical Development: Gimeracil is used in drug formulation to enhance the effectiveness of certain medications, making it valuable in the development of new therapeutic agents.
  • Metabolic Studies: Researchers employ Gimeracil to investigate metabolic pathways and enzyme interactions, providing insights into disease mechanisms and potential treatments.
  • Neuroscience: Its role in modulating neurotransmitter levels makes it a candidate for studies related to neurodegenerative diseases, offering hope for new treatment strategies.
  • Clinical Trials: Gimeracil is frequently included in clinical trials aimed at assessing its efficacy and safety, contributing to advancements in medical science and patient care.

Citas