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Catalog Number:
38275
CAS Number:
133-67-5
Trichlorométhiazide
Purity:
≥ 99 % (dosage par titration)
Synonym(s):
6-Chloro-3-dichlorométhyl-3,4-dihydro-2 H -1,2,4-benzothiadiazine-7-sulfonamide1,1-Dioxyde
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$221.63 /10G
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Product Information

Trichloromethiazide is a potent thiazide diuretic widely utilized in the treatment of hypertension and edema associated with various medical conditions, including heart failure and kidney disorders. This compound functions by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, promoting increased urine output and effectively lowering blood pressure. Its unique chemical structure allows for enhanced solubility and bioavailability, making it a preferred choice among healthcare professionals.

In addition to its primary applications in cardiovascular health, Trichloromethiazide is also explored in research settings for its potential role in managing conditions like diabetes insipidus and certain types of kidney stones. Its efficacy in promoting electrolyte balance while minimizing potassium loss distinguishes it from other diuretics, making it a valuable asset in therapeutic regimens. Researchers and clinicians appreciate its versatility and effectiveness, ensuring that Trichloromethiazide remains a staple in both clinical and laboratory environments.

Synonyms
6-Chloro-3-dichlorométhyl-3,4-dihydro-2 H -1,2,4-benzothiadiazine-7-sulfonamide1,1-Dioxyde
CAS Number
133-67-5
Purity
≥ 99 % (dosage par titration)
Molecular Formula
C8H8Cl3N3O4S2
Molecular Weight
380.64
MDL Number
MFCD00057315
PubChem ID
5560
Appearance
Poudre blanche à presque blanche à cristal
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
6-Chloro-3-dichlorométhyl-3,4-dihydro-2 H -1,2,4-benzothiadiazine-7-sulfonamide1,1-Dioxyde
CAS Number
133-67-5
Purity
≥ 99 % (dosage par titration)
Molecular Formula
C8H8Cl3N3O4S2
Molecular Weight
380.64
MDL Number
MFCD00057315
PubChem ID
5560
Appearance
Poudre blanche à presque blanche à cristal
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Trichloromethiazide is widely utilized in research focused on:

  • Hypertension Treatment: It is commonly used as a diuretic in the management of high blood pressure, helping to reduce fluid retention and lower blood pressure effectively.
  • Heart Failure Management: This compound is beneficial in treating heart failure by decreasing the workload on the heart through fluid elimination, improving patient outcomes.
  • Kidney Function Studies: In research settings, it aids in studying renal function and electrolyte balance, providing insights into kidney health and disease.
  • Pharmaceutical Formulations: It is incorporated into various drug formulations, enhancing their efficacy in treating cardiovascular conditions.
  • Veterinary Medicine: Trichloromethiazide is also used in veterinary practices for managing fluid retention in animals, showcasing its versatility across species.

Citations