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Poly-L-lysine solution (0.1 % (w/v) in H2O) is widely utilized in research focused on:
- Cell Culture: This compound is commonly used as a coating agent for cell culture dishes, enhancing cell adhesion and growth. It is particularly beneficial for primary cells and stem cells, which require a conducive environment for optimal proliferation.
- Drug Delivery Systems: Poly-L-lysine is employed in the formulation of nanoparticles for targeted drug delivery. Its positive charge facilitates the encapsulation of negatively charged drugs, improving bioavailability and therapeutic efficacy.
- Biotechnology Applications: In the field of biotechnology, it serves as a transfection agent, aiding in the introduction of nucleic acids into cells. This is crucial for gene therapy and vaccine development, where efficient delivery is essential.
- Biomedical Research: Researchers utilize this compound in various assays, including enzyme-linked immunosorbent assays (ELISA) and immunohistochemistry, to enhance the binding of antibodies to surfaces, improving sensitivity and specificity of detection.
- Surface Modification: Poly-L-lysine is used to modify surfaces of biomaterials, improving their biocompatibility. This application is vital in the development of implants and prosthetics, ensuring better integration with biological tissues.
General Information
Properties
Safety and Regulations
Applications
Poly-L-lysine solution (0.1 % (w/v) in H2O) is widely utilized in research focused on:
- Cell Culture: This compound is commonly used as a coating agent for cell culture dishes, enhancing cell adhesion and growth. It is particularly beneficial for primary cells and stem cells, which require a conducive environment for optimal proliferation.
- Drug Delivery Systems: Poly-L-lysine is employed in the formulation of nanoparticles for targeted drug delivery. Its positive charge facilitates the encapsulation of negatively charged drugs, improving bioavailability and therapeutic efficacy.
- Biotechnology Applications: In the field of biotechnology, it serves as a transfection agent, aiding in the introduction of nucleic acids into cells. This is crucial for gene therapy and vaccine development, where efficient delivery is essential.
- Biomedical Research: Researchers utilize this compound in various assays, including enzyme-linked immunosorbent assays (ELISA) and immunohistochemistry, to enhance the binding of antibodies to surfaces, improving sensitivity and specificity of detection.
- Surface Modification: Poly-L-lysine is used to modify surfaces of biomaterials, improving their biocompatibility. This application is vital in the development of implants and prosthetics, ensuring better integration with biological tissues.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Numéro de catalogue
Numéro de lot/série
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
Numéro de catalogue
Numéro de lot/série
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Numéro de catalogue
Numéro de lot/série
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.