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Catalog Number:
31674
CAS Number:
1887209-51-9
Fmoc- cis -4-méthylthio-Pro-OH
Purity:
≥ 99 % (HPLC)
Synonym(s):
Acide ( 2 S,4 S )-Fmoc-4-méthylthio-pyrrolidine-2-carboxylique
Documents
$86.23 /100 mg
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Product Information

Fmoc-cis-4-methylthio-Pro-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique cis configuration and the presence of a methylthio group enhance its reactivity and stability, making it an attractive choice for researchers aiming to develop complex peptide structures.

In practical applications, Fmoc-cis-4-methylthio-Pro-OH is particularly valuable in the pharmaceutical industry for the synthesis of bioactive peptides and therapeutic agents. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups allows for the efficient assembly of peptides with desired biological activities. Additionally, this compound is beneficial in the development of peptide-based drugs, where precise control over stereochemistry is crucial. Researchers can leverage its unique properties to create innovative solutions in drug discovery and development.

Synonyms
Acide ( 2 S,4 S )-Fmoc-4-méthylthio-pyrrolidine-2-carboxylique
CAS Number
1887209-51-9
Purity
≥ 99 % (HPLC)
Molecular Formula
C 21 H 21 NON 4 S
Molecular Weight
383.46
MDL Number
MFCD30749170
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -40 ± 2° (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Acide ( 2 S,4 S )-Fmoc-4-méthylthio-pyrrolidine-2-carboxylique
CAS Number
1887209-51-9
Purity
≥ 99 % (HPLC)
Molecular Formula
C 21 H 21 NON 4 S
Molecular Weight
383.46
MDL Number
MFCD30749170
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -40 ± 2° (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-cis-4-methylthio-Pro-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It is employed in the design of peptide-based therapeutics, where its unique properties enhance the stability and bioactivity of drug candidates, making it valuable in pharmaceutical research.
  • Bioconjugation: The compound is useful in bioconjugation techniques, where it can be attached to biomolecules, facilitating the development of targeted drug delivery systems and diagnostic agents.
  • Research in Protein Engineering: Researchers utilize this compound to modify proteins, improving their functionality and stability, which is crucial for applications in biotechnology and enzyme design.
  • Analytical Chemistry: It is applied in analytical methods to study protein interactions and conformational changes, providing insights into biochemical processes that are essential for various scientific investigations.

Citations