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Catalog Number:
02451
CAS Number:
135837-63-7
Fmoc-3,4-déhydro-L-proline
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-3,4-déhydro-L-Pro-OH, ( Acide S -Fmoc-3,4-déhydro-pyrrolidine-2-carboxylique
Documents
$120.88 /100 mg
Taille
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Product Information

Fmoc-3,4-dehydro-L-proline is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for the incorporation of dehydroproline into peptides, enhancing their stability and bioactivity. Researchers and industry professionals appreciate its role in the development of cyclic peptides and peptidomimetics, which are crucial in medicinal chemistry for creating compounds with improved pharmacological properties.

In addition to its applications in peptide synthesis, Fmoc-3,4-dehydro-L-proline is also valuable in the study of protein folding and function. Its ability to mimic natural amino acids while providing distinct conformational features makes it an important tool in structural biology. The compound's stability and compatibility with various coupling reagents further enhance its utility in complex peptide synthesis, making it a preferred choice for researchers aiming to develop novel therapeutics.

Synonyms
Fmoc-3,4-déhydro-L-Pro-OH, ( Acide S -Fmoc-3,4-déhydro-pyrrolidine-2-carboxylique
CAS Number
135837-63-7
Purity
≥ 98 % (HPLC)
Molecular Formula
C 20 H 174
Molecular Weight
335.4
MDL Number
MFCD00151940
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Fmoc-3,4-déhydro-L-Pro-OH, ( Acide S -Fmoc-3,4-déhydro-pyrrolidine-2-carboxylique
CAS Number
135837-63-7
Purity
≥ 98 % (HPLC)
Molecular Formula
C 20 H 174
Molecular Weight
335.4
MDL Number
MFCD00151940
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-3,4-dehydro-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities.
  • Drug Development: Its unique properties make it valuable in the design of pharmaceuticals, particularly in developing compounds that target specific biological pathways.
  • Bioconjugation: Fmoc-3,4-dehydro-L-proline is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules for enhanced therapeutic effects.
  • Protein Engineering: Researchers leverage this compound to modify proteins, improving their stability and activity, which is crucial in various biotechnological applications.
  • Research in Structural Biology: It aids in the study of protein structures and interactions, contributing to a better understanding of biological mechanisms and potential drug targets.

Citations