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Catalog Number:
04128
CAS Number:
205526-25-6
Fmoc-3,5-difluoro-D-phénylalanine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-D-Phe(3,5-DiF)-OH, Fmoc-3,5-difluoro-D-Phe-OH
Documents
$65.00 /250 mg
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Product Information

Fmoc-3,5-difluoro-D-phenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique difluorophenyl group, which enhances its biochemical properties, making it an excellent choice for researchers focused on developing novel therapeutics. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for efficient coupling reactions, facilitating the synthesis of complex peptides with improved stability and bioactivity.

In pharmaceutical research, Fmoc-3,5-difluoro-D-phenylalanine is particularly relevant for designing peptide-based drugs that require specific structural characteristics for optimal efficacy. Its application extends to the development of inhibitors and modulators in various biological pathways, showcasing its potential in advancing therapeutic strategies. Researchers appreciate its ability to improve the pharmacokinetic profiles of peptide drugs, making it a preferred choice in the field of medicinal chemistry.

Synonyms
Fmoc-D-Phe(3,5-DiF)-OH, Fmoc-3,5-difluoro-D-Phe-OH
CAS Number
205526-25-6
Purity
≥ 99 % (HPLC)
Molecular Formula
C 24 H 19 F 2 NON 4
Molecular Weight
423.4
MDL Number
MFCD00797580
PubChem ID
53394996
Melting Point
150 - 155 °C
Appearance
Poudre cristalline blanc cassé
Optical Rotation
[a] 20 D = 43 ± 2 ° (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(3,5-DiF)-OH, Fmoc-3,5-difluoro-D-Phe-OH
CAS Number
205526-25-6
Purity
≥ 99 % (HPLC)
Molecular Formula
C 24 H 19 F 2 NON 4
Molecular Weight
423.4
MDL Number
MFCD00797580
PubChem ID
53394996
Melting Point
150 - 155 °C
Appearance
Poudre cristalline blanc cassé
Optical Rotation
[a] 20 D = 43 ± 2 ° (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-3,5-difluoro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing chemists to create complex peptides with high specificity and yield.
  • Drug Development: Its unique fluorinated structure can enhance the pharmacological properties of peptide-based drugs, making them more effective in targeting specific biological pathways.
  • Bioconjugation: Researchers use this compound to facilitate the attachment of biomolecules to surfaces or other molecules, which is essential in developing biosensors and drug delivery systems.
  • Fluorine-Containing Compounds: The incorporation of fluorine can improve the stability and bioavailability of compounds, making it valuable in medicinal chemistry for creating more effective therapeutics.
  • Research on Protein Interactions: This compound can be used to study protein-ligand interactions, providing insights into biological mechanisms and aiding in the design of new inhibitors.

Citations