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Catalog Number:
15258
CAS Number:
220498-04-4
Acide Fmoc-( R -3-amino-3-(4-bromophényl)propionique
Synonym(s):
Fmoc-D-β-Phe(4-Br)-OH, ( R -Fmoc-4-bromo-β-phénylalanine
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Product Information

Fmoc-(R)-3-amino-3-(4-bromophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its specific structure, characterized by the presence of a bromophenyl moiety, enhances its reactivity and allows for the introduction of diverse functionalities, making it an invaluable tool for researchers in drug development and materials science.

In practical applications, Fmoc-(R)-3-amino-3-(4-bromophenyl)propionic acid is particularly beneficial in the design of bioactive peptides and pharmaceuticals, where precise control over amino acid sequences is crucial. Its ability to facilitate the incorporation of bromine into peptide chains opens avenues for the development of novel therapeutic agents with improved efficacy and selectivity. Researchers appreciate its reliability and efficiency in synthesizing complex molecular architectures, thereby accelerating the pace of innovation in drug discovery and development.

Synonyms
Fmoc-D-β-Phe(4-Br)-OH, ( R -Fmoc-4-bromo-β-phénylalanine
CAS Number
220498-04-4
Molecular Formula
C24H20BrNO4
Molecular Weight
466.33
MDL Number
MFCD01311784
PubChem ID
2759183
Conditions
Conserver à 0-8°C
General Information
Synonyms
Fmoc-D-β-Phe(4-Br)-OH, ( R -Fmoc-4-bromo-β-phénylalanine
CAS Number
220498-04-4
Molecular Formula
C24H20BrNO4
Molecular Weight
466.33
MDL Number
MFCD01311784
PubChem ID
2759183
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(4-bromophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, where its Fmoc protecting group allows for easy deprotection and subsequent coupling reactions.
  • Drug Development: Its unique structure makes it valuable in the design of novel pharmaceutical compounds, especially in targeting specific biological pathways, enhancing the efficacy of drug candidates.
  • Bioconjugation: The compound can be used in bioconjugation techniques, linking biomolecules to therapeutic agents, which is crucial in developing targeted therapies and improving drug delivery systems.
  • Research in Neuroscience: Due to its structural properties, it is employed in studies related to neurotransmitter systems, potentially aiding in the development of treatments for neurological disorders.
  • Material Science: Its application extends to the development of functional materials, where it can be incorporated into polymers or coatings to impart specific properties, such as enhanced biocompatibility or targeted drug release.

Citations