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Catalog Number:
15297
CAS Number:
269398-86-9
Fmoc-4-méthyl-D-β-homophénylalanine
Purity:
≥ 99 % (HPLC, pureté chirale)
Synonym(s):
Fmoc-D-β-HomoPhe(4-Me)-OH, Acide Fmoc-( R -3-amino-4-(4-méthylphényl)butyrique
Documents
$72.31 /100 mg
Taille
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Product Information

Fmoc-4-methyl-D-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of complex peptides. Its unique structure, characterized by a 4-methylphenyl side chain, enhances the hydrophobic interactions, making it particularly useful in the formation of stable peptide structures. Researchers and industry professionals appreciate its role in solid-phase peptide synthesis, where it contributes to the efficient assembly of peptides with specific biological activities.

The practical applications of Fmoc-4-methyl-D-b-homophenylalanine extend to the pharmaceutical industry, particularly in the development of peptide-based therapeutics and vaccines. Its ability to facilitate the synthesis of modified peptides allows for the exploration of new drug candidates with improved efficacy and selectivity. Additionally, this compound's stability and compatibility with various coupling reagents make it a preferred choice for chemists looking to optimize their synthetic routes. With its proven track record in peptide chemistry, Fmoc-4-methyl-D-b-homophenylalanine stands out as a valuable tool for advancing research and development in biochemistry and medicinal chemistry.

Synonyms
Fmoc-D-β-HomoPhe(4-Me)-OH, Acide Fmoc-( R -3-amino-4-(4-méthylphényl)butyrique
CAS Number
269398-86-9
Purity
≥ 99 % (HPLC, pureté chirale)
Molecular Formula
C 26 H 254
Molecular Weight
415.49
MDL Number
MFCD01860929
PubChem ID
53397954
Melting Point
133-139 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 23 = +20 ± 2º (C=1, dans DMF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Fmoc-D-β-HomoPhe(4-Me)-OH, Acide Fmoc-( R -3-amino-4-(4-méthylphényl)butyrique
CAS Number
269398-86-9
Purity
≥ 99 % (HPLC, pureté chirale)
Molecular Formula
C 26 H 254
Molecular Weight
415.49
MDL Number
MFCD01860929
PubChem ID
53397954
Melting Point
133-139 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 23 = +20 ± 2º (C=1, dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-4-methyl-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing novel therapeutics, especially those targeting specific biological pathways, enhancing efficacy and selectivity.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach drugs or imaging agents to biomolecules, improving the delivery and effectiveness of treatments.
  • Research in Neuroscience: It plays a role in studying neuropeptides, contributing to the understanding of neurological functions and disorders, which can lead to new treatment strategies.
  • Custom Peptide Libraries: Researchers utilize this compound to create diverse peptide libraries for screening potential drug candidates, facilitating faster discovery and development processes.

Citations