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Catalog Number:
15541
CAS Number:
511272-50-7
Acide Fmoc-( R -3-amino-3-(2-fluorophényl)propionique
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-β-Phe(2-F)-OH, ( R -Fmoc-2-fluoro-β-phénylalanine
Documents
$65.40 /250 mg
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Product Information

Fmoc-(R)-3-amino-3-(2-fluorophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and pharmaceutical research. This compound features a fluorinated aromatic ring, which enhances its bioactivity and stability, making it an ideal candidate for developing novel therapeutic agents. Its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection under mild conditions, facilitating the synthesis of complex peptides with high purity and yield. Researchers in medicinal chemistry and biochemistry can leverage this compound to create targeted drug candidates, particularly in the development of peptide-based therapeutics that require precise amino acid sequences.

In addition to its applications in drug discovery, Fmoc-(R)-3-amino-3-(2-fluorophenyl)propionic acid is also valuable in the study of protein interactions and enzyme activity. Its structural properties enable the exploration of structure-activity relationships, providing insights that can lead to the optimization of lead compounds. This compound stands out for its ability to enhance the pharmacological profiles of peptides, making it a preferred choice for researchers aiming to innovate in the field of peptide chemistry.

Synonyms
Fmoc-D-β-Phe(2-F)-OH, ( R -Fmoc-2-fluoro-β-phénylalanine
CAS Number
511272-50-7
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 20 FNO 4
Molecular Weight
405.42
MDL Number
MFCD03428031
PubChem ID
2759192
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 25 = +23 ± 2º (C = 1 % dans DMF)
Conditions
Conserver à 0-8°C
General Information
Synonyms
Fmoc-D-β-Phe(2-F)-OH, ( R -Fmoc-2-fluoro-β-phénylalanine
CAS Number
511272-50-7
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 20 FNO 4
Molecular Weight
405.42
MDL Number
MFCD03428031
PubChem ID
2759192
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 25 = +23 ± 2º (C = 1 % dans DMF)
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(2-fluorophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting the overall structure. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its unique fluorophenyl group enhances the bioactivity of peptides, making it valuable in the design of new drugs with improved efficacy and specificity in targeting diseases.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules to therapeutic agents, which is essential in creating targeted therapies in cancer treatment.
  • Research in Neuroscience: Due to its structural properties, it is employed in studies related to neurotransmitter systems, aiding in the development of treatments for neurological disorders.
  • Analytical Chemistry: It is utilized in analytical methods to study protein interactions and stability, providing insights into protein behavior that are critical for various biotechnological applications.

Citations