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Catalog Number:
29360
CAS Number:
288617-76-5
Fmoc-α-méthyl-D-allylglycine
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-α-Me-D-Gly(allyl)-OH, Acide Fmoc-( R -2-amino-2-méthyl-4-penténoïque
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Product Information

Fmoc-a-methyl-D-allylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of complex peptides. Its unique structure, characterized by the presence of a methyl group and an allyl side chain, enhances its reactivity and stability, making it an ideal choice for researchers seeking to create novel peptide sequences with improved pharmacological properties.

In the pharmaceutical industry, Fmoc-a-methyl-D-allylglycine is particularly valuable for the development of peptide-based therapeutics, where it can be employed to introduce specific functionalities or to modulate biological activity. Its ability to facilitate the synthesis of cyclic peptides and other complex structures opens up new avenues for drug discovery and development. Researchers appreciate its compatibility with various coupling reagents and its efficiency in solid-phase peptide synthesis, ensuring high yields and purity in their final products.

Synonyms
Fmoc-α-Me-D-Gly(allyl)-OH, Acide Fmoc-( R -2-amino-2-méthyl-4-penténoïque
CAS Number
288617-76-5
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 21 H 214
Molecular Weight
351.4
MDL Number
MFCD08063323
PubChem ID
53398096
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = 2 ± 1 º (C = 1 dans EtOH)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-α-Me-D-Gly(allyl)-OH, Acide Fmoc-( R -2-amino-2-méthyl-4-penténoïque
CAS Number
288617-76-5
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 21 H 214
Molecular Weight
351.4
MDL Number
MFCD08063323
PubChem ID
53398096
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = 2 ± 1 º (C = 1 dans EtOH)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-a-methyl-D-allylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with enhanced stability.
  • Drug Development: It plays a significant role in the development of pharmaceutical compounds, particularly in designing inhibitors and modulators that target specific biological pathways, thereby aiding in the creation of more effective medications.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps in attaching biomolecules to drugs or diagnostic agents, improving their delivery and efficacy in therapeutic applications.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research for their potential to modulate neurotransmitter systems, which can lead to advancements in treatments for neurological disorders.
  • Custom Synthesis: Researchers often utilize this compound for custom synthesis projects, providing flexibility in designing specific compounds tailored to their experimental needs, thus enhancing research outcomes.

Citations