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Catalog Number:
00180
CAS Number:
6341-24-8
D-Histidine hydrochloride monohydrate
Purity:
≥ 98% (TLC)
Synonym(s):
D-His-OH·HCl·H2O
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Product Information

D-Histidine hydrochloride monohydrate is a vital amino acid derivative known for its unique properties and applications in various fields. This compound serves as a crucial building block in protein synthesis and is particularly valued in biochemical research and pharmaceutical formulations. Its ability to act as a precursor for histamine makes it significant in studies related to immune response and neurotransmission. Researchers often utilize D-Histidine hydrochloride monohydrate in the development of peptide-based drugs and nutritional supplements, enhancing the bioavailability of histidine in formulations.

In addition to its role in research, D-Histidine hydrochloride monohydrate is also employed in the food industry as a flavor enhancer and preservative, owing to its antioxidant properties. Its solubility in water and stability under various conditions make it an ideal candidate for diverse applications, including cell culture media and enzyme assays. The compound's unique characteristics, such as its imidazole side chain, provide it with advantages over other amino acids, making it a preferred choice for professionals seeking reliable and effective solutions in their projects.

Synonyms
D-His-OH·HCl·H2O
CAS Number
6341-24-8
Purity
≥ 98% (TLC)
Molecular Formula
C6H9N3O2·HCl·H2O
Molecular Weight
209.6
MDL Number
MFCD00150081
PubChem ID
5351508
Melting Point
252 - 256 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D = - 9 ± 2º (C = 1 in 6N HCl)
Conditions
Store at RT
General Information
Synonyms
D-His-OH·HCl·H2O
CAS Number
6341-24-8
Purity
≥ 98% (TLC)
Molecular Formula
C6H9N3O2·HCl·H2O
Molecular Weight
209.6
MDL Number
MFCD00150081
PubChem ID
5351508
Melting Point
252 - 256 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D = - 9 ± 2º (C = 1 in 6N HCl)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

D-Histidine hydrochloride monohydrate is widely utilized in research focused on:

  • Biochemical Research: It serves as a building block for peptide synthesis, enabling scientists to create specific peptides for studying protein interactions and functions.
  • Pharmaceutical Development: This compound is used in drug formulation, particularly in medications targeting neurological disorders, due to its role in histamine regulation.
  • Nutrition and Dietary Supplements: It is incorporated into supplements aimed at enhancing athletic performance and recovery, as histidine is essential for muscle metabolism.
  • Cell Culture Media: D-Histidine hydrochloride is added to cell culture media to support the growth of various cell types, improving the yield and viability of cultured cells.
  • Analytical Chemistry: It is employed as a standard in chromatographic techniques, helping researchers accurately quantify histidine levels in biological samples.

Citations