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Catalog Number:
00923
CAS Number:
6553-96-4
2,4,6-Triisopropylbenzenesulfonyl chloride
Purity:
≥ 99% (Titration)
Synonym(s):
Trisyl chloride
Hazmat
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Product Information

2,4,6-Triisopropylbenzenesulfonyl chloride is a versatile sulfonyl chloride compound known for its significant role in organic synthesis and pharmaceutical applications. This compound features a unique triisopropyl substitution on the benzene ring, which enhances its reactivity and solubility in various organic solvents. It is widely utilized in the synthesis of sulfonamides and other sulfonyl derivatives, making it a valuable reagent for researchers and industry professionals engaged in drug development and chemical research.

The compound's ability to act as a sulfonylating agent allows for the introduction of sulfonyl groups into target molecules, facilitating the creation of complex structures with improved biological activity. Its stability and ease of handling make it an ideal choice for laboratories focused on synthesizing novel compounds. Additionally, 2,4,6-Triisopropylbenzenesulfonyl chloride is recognized for its efficiency in reactions, often leading to higher yields compared to similar sulfonyl chlorides. This makes it a preferred reagent for chemists looking to optimize their synthetic pathways.

Synonyms
Trisyl chloride
CAS Number
6553-96-4
Purity
≥ 99% (Titration)
Molecular Formula
C15H23SO2Cl
Molecular Weight
302.9
MDL Number
MFCD00007433
PubChem ID
81042
Melting Point
93-97 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
Trisyl chloride
CAS Number
6553-96-4
Purity
≥ 99% (Titration)
Molecular Formula
C15H23SO2Cl
Molecular Weight
302.9
MDL Number
MFCD00007433
PubChem ID
81042
Melting Point
93-97 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,4,6-Triisopropylbenzenesulfonyl chloride is widely utilized in research focused on:

  • Synthetic Chemistry: This compound serves as a versatile reagent in the synthesis of sulfonamides and other sulfonyl-containing compounds, which are important in pharmaceuticals and agrochemicals.
  • Pharmaceutical Development: It is used in the preparation of various active pharmaceutical ingredients (APIs), enhancing the efficiency of drug design by providing a pathway for functional group modifications.
  • Polymer Chemistry: The compound acts as a coupling agent in the production of specialty polymers, improving the properties of materials used in coatings, adhesives, and sealants.
  • Analytical Chemistry: It is employed in the derivatization of amines and alcohols, facilitating their detection and quantification in complex mixtures through chromatographic techniques.
  • Bioconjugation: This chemical is utilized in bioconjugation reactions, allowing for the attachment of biomolecules to surfaces or other molecules, which is crucial in the development of biosensors and targeted drug delivery systems.

Citations