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Catalog Number:
01353
CAS Number:
62965-35-9
Boc-L-α-tert-butylglycine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-α-tert-butyl-Gly-OH, Boc-L-Tle-OH
Documents
$18.53 /1G
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Product Information

Boc-L-a-tert-butylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butyl protective group, which enhances its stability and solubility, making it an ideal choice for researchers looking to develop complex peptides with improved bioactivity. Its unique structure allows for the introduction of chirality in peptide chains, facilitating the design of novel therapeutics and biologically active compounds.

In the pharmaceutical industry, Boc-L-a-tert-butylglycine serves as a key building block in the synthesis of various bioactive peptides, including those used in drug development and delivery systems. Its application extends to the fields of biochemistry and molecular biology, where it is employed in the study of protein interactions and enzyme activity. The compound's favorable properties, such as its ease of handling and compatibility with various coupling reagents, make it a preferred choice for professionals seeking reliable and efficient solutions in peptide synthesis.

Synonyms
Boc-L-α-tert-butyl-Gly-OH, Boc-L-Tle-OH
CAS Number
62965-35-9
Purity
≥ 98% (HPLC)
Molecular Formula
C11H21NO4
Molecular Weight
231.3
MDL Number
MFCD00065574
PubChem ID
5046859
Melting Point
110 - 121 °C
Appearance
White powder
Optical Rotation
[a]D20 = -4.2 ± 1 ° (C=1 in AcOH) [a]D20 = -8 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-α-tert-butyl-Gly-OH, Boc-L-Tle-OH
CAS Number
62965-35-9
Purity
≥ 98% (HPLC)
Molecular Formula
C11H21NO4
Molecular Weight
231.3
MDL Number
MFCD00065574
PubChem ID
5046859
Melting Point
110 - 121 °C
Appearance
White powder
Optical Rotation
[a]D20 = -4.2 ± 1 ° (C=1 in AcOH) [a]D20 = -8 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-a-tert-butylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing chemists to selectively modify amino acids without affecting others, which is crucial for creating complex biological molecules.
  • Drug Development: Its unique structure makes it valuable in the design of pharmaceuticals, particularly in optimizing the properties of drug candidates, enhancing their stability and bioavailability.
  • Bioconjugation: Researchers use it to create bioconjugates, linking biomolecules with drugs or imaging agents, which is essential in targeted therapy and diagnostics in medicine.
  • Protein Engineering: The compound is employed in modifying proteins to study their functions and interactions, aiding in the development of novel enzymes and therapeutic proteins.
  • Research in Neuroscience: Its derivatives are explored in studies related to neurotransmitter systems, contributing to the understanding of neurological disorders and potential treatments.

Citations