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Catalog Number:
01773
CAS Number:
100564-78-1
Boc-L-homophenylalanine
Purity:
≥ 98% (Assay)
Synonym(s):
Boc-L-HomoPhe-OH, (S-2-(Boc-amino)-4-phenylbutyric acid, Boc-HomoPhe-OH
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Product Information

Boc-L-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an excellent choice for various synthetic applications. Researchers often employ Boc-L-homophenylalanine in the development of peptide-based drugs, particularly in the design of bioactive peptides that can mimic natural proteins. Its unique structure allows for the incorporation of phenylalanine-like properties, which can be crucial in studies related to protein folding and function.

In addition to its role in peptide synthesis, Boc-L-homophenylalanine is also valuable in the field of medicinal chemistry, where it serves as a building block for the creation of novel therapeutic agents. Its ability to facilitate the introduction of hydrophobic side chains into peptides enhances the pharmacological profiles of the resulting compounds. This makes Boc-L-homophenylalanine an essential tool for researchers aiming to optimize drug efficacy and specificity in various therapeutic areas.

Synonyms
Boc-L-HomoPhe-OH, (S-2-(Boc-amino)-4-phenylbutyric acid, Boc-HomoPhe-OH
CAS Number
100564-78-1
Purity
≥ 98% (Assay)
Molecular Formula
C15H21NO4
Molecular Weight
279.33
MDL Number
MFCD00076904
PubChem ID
7018726
Melting Point
70 - 80 °C
Appearance
White crystals or crystalline powder
Optical Rotation
[a]20D = 5.5 - 7.5 º (C=2 in Ethanol)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-HomoPhe-OH, (S-2-(Boc-amino)-4-phenylbutyric acid, Boc-HomoPhe-OH
CAS Number
100564-78-1
Purity
≥ 98% (Assay)
Molecular Formula
C15H21NO4
Molecular Weight
279.33
MDL Number
MFCD00076904
PubChem ID
7018726
Melting Point
70 - 80 °C
Appearance
White crystals or crystalline powder
Optical Rotation
[a]20D = 5.5 - 7.5 º (C=2 in Ethanol)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-homophenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound is a valuable building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds. Its protective Boc group allows for selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Development: Researchers leverage Boc-L-homophenylalanine in drug design to create novel therapeutic agents. Its unique structural properties can improve the bioactivity and selectivity of drug candidates, making it a preferred choice in medicinal chemistry.
  • Protein Engineering: In the field of biotechnology, this compound is used to modify protein structures. By incorporating it into proteins, scientists can study the effects of amino acid substitutions on protein function, stability, and interactions.
  • Bioconjugation: Boc-L-homophenylalanine serves as a key component in bioconjugation techniques, where it can be used to attach biomolecules to surfaces or other molecules. This application is crucial in developing targeted drug delivery systems and diagnostic tools.
  • Research in Neuroscience: Its structural similarity to phenylalanine allows researchers to investigate its role in neurotransmitter pathways, contributing to studies on neurological disorders and potential treatments.

Citations