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Catalog Number:
02230
CAS Number:
65147-22-0
Z-Phe-Arg-AMC·HCl
Purity:
≥ 99% (TLC)
Documents
$86.23 /5MG
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Product Information

Z-Phe-Arg-AMC·HCl is a highly valuable compound in the realm of biochemical research and pharmaceutical applications. This peptide substrate is particularly recognized for its role in studying protease activity, making it an essential tool for researchers focused on enzyme kinetics and protein interactions. Its unique structure allows for effective fluorescence-based assays, enabling scientists to monitor proteolytic activity with high sensitivity and specificity. The hydrochloride salt form enhances its solubility, facilitating easier handling and application in laboratory settings.

In addition to its utility in protease assays, Z-Phe-Arg-AMC·HCl is also employed in drug discovery processes, particularly in the development of therapeutic agents targeting various diseases. Its ability to serve as a substrate for specific proteases makes it invaluable in screening for inhibitors, thus aiding in the identification of potential drug candidates. Researchers in both academic and industrial settings will find this compound indispensable for advancing their studies in enzymology and medicinal chemistry.

CAS Number
65147-22-0
Purity
≥ 99% (TLC)
Molecular Formula
C33H36N6O6·HCl
Molecular Weight
649.15
MDL Number
MFCD00077030
PubChem ID
5047642
Melting Point
178-182 ºC
Appearance
White powder
Optical Rotation
+13.8° (c=2% EtOH)
Conditions
Store at ≤ -15 °C
General Information
CAS Number
65147-22-0
Purity
≥ 99% (TLC)
Molecular Formula
C33H36N6O6·HCl
Molecular Weight
649.15
MDL Number
MFCD00077030
PubChem ID
5047642
Melting Point
178-182 ºC
Appearance
White powder
Optical Rotation
+13.8° (c=2% EtOH)
Conditions
Store at ≤ -15 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-Phe-Arg-AMC·HCl is widely utilized in research focused on:

  • Protease Activity Assays: This compound serves as a substrate in assays to measure protease activity, which is crucial for understanding various biological processes and disease mechanisms.
  • Drug Development: Its ability to mimic peptide bonds makes it valuable in the pharmaceutical industry for developing new drugs targeting proteolytic enzymes, enhancing therapeutic efficacy.
  • Biochemical Research: Researchers use it to study enzyme kinetics and inhibition, providing insights into enzyme function and potential therapeutic targets.
  • Diagnostics: The compound can be employed in diagnostic assays to detect specific proteases related to diseases, aiding in early diagnosis and treatment strategies.
  • Biotechnology: In biotechnology, it is used in the production of recombinant proteins, facilitating the study of protein interactions and functions in various applications.

Citations