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Catalog Number:
02407
CAS Number:
112898-00-7
Fmoc-D-glutamine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Gln-OH
Documents
$22.03 /1G
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Product Information

Fmoc-D-glutamine is a versatile amino acid derivative widely utilized in peptide synthesis and biochemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of the amino group during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an essential building block for researchers in the fields of drug development and protein engineering. Fmoc-D-glutamine is particularly valuable in the synthesis of peptides that require specific stereochemistry, as it maintains the integrity of the D-configuration throughout the process.

In addition to its role in peptide synthesis, Fmoc-D-glutamine has applications in the development of pharmaceuticals and bioconjugates. Its stability and compatibility with various coupling reagents enhance its utility in complex synthesis pathways. Researchers appreciate its ability to facilitate the production of high-purity peptides, which are critical for therapeutic applications. With its proven track record in both academic and industrial settings, Fmoc-D-glutamine stands out as a reliable choice for professionals seeking to advance their work in peptide chemistry.

Synonyms
Fmoc-D-Gln-OH
CAS Number
112898-00-7
Purity
≥ 99% (HPLC)
Molecular Formula
C20H20N2O5
Molecular Weight
368.4
MDL Number
MFCD00062959
PubChem ID
100114
Melting Point
213-219 ºC
Appearance
White crystals
Optical Rotation
[a]D20 = 21 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Gln-OH
CAS Number
112898-00-7
Purity
≥ 99% (HPLC)
Molecular Formula
C20H20N2O5
Molecular Weight
368.4
MDL Number
MFCD00062959
PubChem ID
100114
Melting Point
213-219 ºC
Appearance
White crystals
Optical Rotation
[a]D20 = 21 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-glutamine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids, which is crucial in developing new therapeutic peptides.
  • Drug Development: It plays a significant role in the pharmaceutical industry for creating drug candidates, particularly in designing compounds that target specific biological pathways.
  • Biotechnology: Researchers use Fmoc-D-glutamine in the production of recombinant proteins, enhancing the efficiency of expression systems in biotechnological applications.
  • Diagnostics: This chemical is valuable in the development of diagnostic tools, particularly in assays that require specific peptide interactions, aiding in disease detection and monitoring.
  • Material Science: It is also explored in the creation of biomaterials, where its properties can be harnessed to develop materials for tissue engineering and regenerative medicine.

Citations