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Catalog Number:
02435
CAS Number:
133970-31-7
Nα-Fmoc-Nε-2-chloro-Z-L-lysine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Lys(2-Cl-Z)-OH
Documents
$29.34 /1G
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Product Information

Na-Fmoc-Ne-2-chloro-Z-L-lysine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is essential for the selective protection of amino groups during the synthesis of complex peptides. Its chlorinated phenyl moiety enhances its reactivity, making it an excellent choice for researchers looking to incorporate specific functionalities into their peptide sequences.

This compound is particularly valuable in the field of medicinal chemistry, where it can be employed to create bioactive peptides with improved stability and efficacy. Its application extends to the development of peptide-based therapeutics and research into protein interactions, providing a robust platform for innovation in drug design. With its favorable properties, Na-Fmoc-Ne-2-chloro-Z-L-lysine stands out as a key reagent for professionals aiming to advance their research and development projects in biochemistry and pharmaceutical sciences.

Synonyms
Fmoc-L-Lys(2-Cl-Z)-OH
CAS Number
133970-31-7
Purity
≥ 99% (HPLC)
Molecular Formula
C29H29N2O6Cl
Molecular Weight
536.99
MDL Number
MFCD00065664
Melting Point
136-138 °C
Appearance
White powder
Optical Rotation
[a]D = -9 to -11º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Lys(2-Cl-Z)-OH
CAS Number
133970-31-7
Purity
≥ 99% (HPLC)
Molecular Formula
C29H29N2O6Cl
Molecular Weight
536.99
MDL Number
MFCD00065664
Melting Point
136-138 °C
Appearance
White powder
Optical Rotation
[a]D = -9 to -11º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-2-chloro-Z-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, enhancing the efficacy and specificity of therapeutic agents.
  • Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, which is crucial in targeted therapies.
  • Research in Protein Engineering: Researchers utilize it to modify lysine residues in proteins, facilitating studies on protein structure and function, and improving protein stability.
  • Development of Diagnostic Tools: Its application in creating peptide probes aids in the development of diagnostic tools, enhancing detection methods in various medical fields.

Citations