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Catalog Number:
02870
CAS Number:
178432-49-0
Fmoc-(3S-1,2,3,4-tetrahydroisoquinoline-7-hydroxy-3-carboxylic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Tic(OH)-OH, Fmoc-7-hydroxy-L-Tic-OH, Fmoc-Tic(OH)-OH
Documents
$50.30 /100MG
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Product Information

Fmoc-(3S)-1,2,3,4-tetrahydroisoquinoline-7-hydroxy-3-carboxylic acid is a versatile compound widely utilized in the field of organic synthesis and medicinal chemistry. This compound, known for its unique structural features, serves as an essential building block in the development of peptide-based therapeutics and complex organic molecules. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection, making it particularly valuable in solid-phase peptide synthesis. Researchers appreciate its stability and compatibility with various coupling reagents, which enhances its utility in synthesizing bioactive peptides and drug candidates.

In addition to its role in peptide synthesis, this compound has potential applications in the development of novel pharmaceuticals targeting neurological disorders, given its structural resemblance to biologically active isoquinoline derivatives. Its hydroxyl and carboxylic acid functional groups contribute to its reactivity, enabling further modifications that can lead to the discovery of new therapeutic agents. With its robust profile and practical applications, Fmoc-(3S)-1,2,3,4-tetrahydroisoquinoline-7-hydroxy-3-carboxylic acid stands out as a key compound for researchers and industry professionals focused on innovative drug development.

Synonyms
Fmoc-L-Tic(OH)-OH, Fmoc-7-hydroxy-L-Tic-OH, Fmoc-Tic(OH)-OH
CAS Number
178432-49-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H21NO5
Molecular Weight
415.4
MDL Number
MFCD00792388
PubChem ID
4687522
Melting Point
185 - 190 °C
Appearance
White to off-white solid
Optical Rotation
[a]D22 = 22 ± 1 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Tic(OH)-OH, Fmoc-7-hydroxy-L-Tic-OH, Fmoc-Tic(OH)-OH
CAS Number
178432-49-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H21NO5
Molecular Weight
415.4
MDL Number
MFCD00792388
PubChem ID
4687522
Melting Point
185 - 190 °C
Appearance
White to off-white solid
Optical Rotation
[a]D22 = 22 ± 1 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(3S)-1,2,3,4-tetrahydroisoquinoline-7-hydroxy-3-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, enhancing the efficiency and yield of peptide chains.
  • Drug Development: It plays a crucial role in the development of pharmaceuticals, particularly in creating compounds that target specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential in diagnostics and therapeutics.
  • Research in Neuroscience: Its derivatives are studied for their potential effects on neurotransmitter systems, contributing to the understanding of neurological disorders.
  • Analytical Chemistry: This chemical aids in the development of analytical methods for detecting and quantifying biological molecules, improving the accuracy of research findings.

Citations