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Catalog Number:
03914
CAS Number:
201532-01-6
Fmoc-S-trityl-D-penicillamine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Pen(Trt)-OH, Fmoc-S-trityl-β,β-dimethyl-D-Cys-OH
Documents
$100.05 /250MG
Pack Size Availability Price
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Product Information

Fmoc-S-trityl-D-penicillamine is a versatile compound widely utilized in peptide synthesis and drug development. This compound, characterized by its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, offers significant advantages in the formation of peptide bonds, making it an essential tool for researchers in the field of medicinal chemistry. Its trityl group enhances stability and solubility, facilitating the purification and characterization of peptides.

In practical applications, Fmoc-S-trityl-D-penicillamine is particularly valuable in the synthesis of bioactive peptides and pharmaceuticals, where it serves as a building block for complex structures. Its ability to selectively protect amino acids allows for the efficient assembly of peptide sequences, which can be crucial in developing therapeutic agents targeting various diseases. Researchers appreciate its compatibility with automated synthesizers, streamlining the synthesis process and improving yield. This compound stands out for its reliability and effectiveness, making it a preferred choice for professionals in the pharmaceutical and biotechnology industries.

Synonyms
Fmoc-D-Pen(Trt)-OH, Fmoc-S-trityl-β,β-dimethyl-D-Cys-OH
CAS Number
201532-01-6
Purity
≥ 98% (HPLC)
Molecular Formula
C39H35NO4S
Molecular Weight
613.72
MDL Number
MFCD00237389
PubChem ID
53350388
Melting Point
84-93 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -32 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Pen(Trt)-OH, Fmoc-S-trityl-β,β-dimethyl-D-Cys-OH
CAS Number
201532-01-6
Purity
≥ 98% (HPLC)
Molecular Formula
C39H35NO4S
Molecular Weight
613.72
MDL Number
MFCD00237389
PubChem ID
53350388
Melting Point
84-93 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -32 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-trityl-D-penicillamine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions and improved yields. It is particularly useful in solid-phase peptide synthesis, where efficiency is crucial.
  • Drug Development: Its unique structure aids in the design of novel pharmaceuticals, especially in the development of drugs targeting specific diseases. Researchers can modify the compound to enhance bioactivity and reduce side effects.
  • Bioconjugation: The compound is employed in bioconjugation processes, linking biomolecules to therapeutic agents. This application is vital in creating targeted drug delivery systems, improving treatment efficacy.
  • Analytical Chemistry: It is used in various analytical techniques, such as chromatography, to separate and identify compounds. Its stability and reactivity make it a reliable choice for researchers needing precise measurements.
  • Material Science: Fmoc-S-trityl-D-penicillamine finds applications in the development of advanced materials, including polymers and nanomaterials, due to its ability to form stable bonds and enhance material properties.

Citations