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Catalog Number:
03917
CAS Number:
111662-65-8
Fmoc-γ-carboxy γ-(di-tert-butyl ester)-D-glutamic acid
Purity:
98+%
Synonym(s):
Fmoc-D-Gla(OtBu)2-OH, Fmoc-γ-carboxy-D-Glu(OtBu)2-OH
Temperature Sensitive
Documents
$106.96 /25MG
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Product Information

Fmoc-g-carboxy g-(di-tert-butyl ester)-D-glutamic acid is a highly versatile compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which is essential for the selective protection of the amine group during solid-phase peptide synthesis. Its unique structure, including the di-tert-butyl ester groups, enhances its stability and solubility, making it an ideal choice for researchers looking to streamline their synthesis processes.

This compound is particularly valuable in the production of peptides with specific functionalities, allowing for the incorporation of D-glutamic acid into complex peptide sequences. Its applications extend to the development of pharmaceuticals, where it plays a crucial role in creating bioactive peptides and proteins. Researchers in the fields of medicinal chemistry and biochemistry will find this compound indispensable for advancing their projects, thanks to its efficiency in facilitating peptide coupling reactions and its compatibility with various coupling agents.

Synonyms
Fmoc-D-Gla(OtBu)2-OH, Fmoc-γ-carboxy-D-Glu(OtBu)2-OH
CAS Number
111662-65-8
Purity
98+%
Molecular Formula
C29H35NO8
Molecular Weight
525.6
MDL Number
MFCD00672341
PubChem ID
5043441
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-D-Gla(OtBu)2-OH, Fmoc-γ-carboxy-D-Glu(OtBu)2-OH
CAS Number
111662-65-8
Purity
98+%
Molecular Formula
C29H35NO8
Molecular Weight
525.6
MDL Number
MFCD00672341
PubChem ID
5043441
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-g-carboxy g-(di-tert-butyl ester)-D-glutamic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptides with high purity and yield.
  • Drug Development: It plays a crucial role in the design of peptide-based therapeutics, particularly in developing drugs targeting specific receptors or enzymes, enhancing their efficacy.
  • Bioconjugation: The chemical is used in bioconjugation techniques, linking peptides to other biomolecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: Its derivatives are employed in studying glutamate receptors, contributing to advancements in understanding neurological disorders and potential treatments.
  • Material Science: The compound is also explored in the development of novel materials, such as hydrogels, which can be used in drug delivery and tissue engineering applications.

Citations