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Catalog Number:
04068
CAS Number:
250384-77-1
Fmoc-L-α-aminoadipic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Aad-OH, Fmoc-L-2-aminohexanedioic acid
Documents
$88.63 /1G
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Product Information

Fmoc-L-a-aminoadipic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential tool for chemists working in the field of organic synthesis and medicinal chemistry. Its unique structure, characterized by a hexanedioic acid backbone, provides enhanced stability and solubility, facilitating its use in various applications, including the development of bioactive peptides and pharmaceuticals.

Researchers appreciate Fmoc-L-a-aminoadipic acid for its ability to enhance the efficiency of peptide coupling reactions, leading to higher yields and purities in the final products. This compound is particularly beneficial in the synthesis of cyclic peptides and other complex structures, where precision and control are paramount. Its compatibility with automated synthesizers further streamlines the synthesis process, making it a preferred choice for both academic and industrial laboratories focused on peptide research and development.

Synonyms
Fmoc-L-Aad-OH, Fmoc-L-2-aminohexanedioic acid
CAS Number
250384-77-1
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO6
Molecular Weight
383.4
MDL Number
MFCD01631983
PubChem ID
23190050
Appearance
White powder
Optical Rotation
[a]D25 = -12.2 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Aad-OH, Fmoc-L-2-aminohexanedioic acid
CAS Number
250384-77-1
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO6
Molecular Weight
383.4
MDL Number
MFCD01631983
PubChem ID
23190050
Appearance
White powder
Optical Rotation
[a]D25 = -12.2 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-a-aminoadipic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice among chemists.
  • Drug Development: In pharmaceutical research, it is used to create novel peptide-based drugs, enhancing bioavailability and efficacy. This is particularly valuable in developing treatments for complex diseases.
  • Bioconjugation: The compound is employed in bioconjugation techniques, linking biomolecules to enhance their functionality. This is crucial in creating targeted therapies and diagnostics in the biomedical field.
  • Protein Engineering: Researchers utilize it to modify proteins, improving their stability and activity. This application is essential in biotechnology for producing more effective enzymes and therapeutic proteins.
  • Research in Neuroscience: It plays a role in studying neuropeptides, contributing to the understanding of neurological functions and potential treatments for neurodegenerative diseases.

Citations