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Catalog Number:
04115
CAS Number:
205526-34-7
Fmoc-4-cyano-D-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Phe(4-CN)-OH, Fmoc-p-cyano-D-Phe-OH
Documents
$60.40 /1G
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Product Information

Fmoc-4-cyano-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of the amino group during solid-phase peptide synthesis. Its unique cyano group enhances the compound's reactivity, making it an excellent choice for researchers looking to introduce specific functionalities into peptides. Fmoc-4-cyano-D-phenylalanine is particularly valuable in the synthesis of bioactive peptides and pharmaceuticals, where precise modifications can lead to improved efficacy and stability.

In addition to its role in peptide synthesis, this compound is also used in the development of novel therapeutic agents, especially in the fields of oncology and neurology. Its ability to facilitate the introduction of diverse side chains allows for the exploration of structure-activity relationships, which is essential for drug discovery. Researchers appreciate the compound's high purity and reliability, making it an indispensable tool in both academic and industrial laboratories.

Synonyms
Fmoc-D-Phe(4-CN)-OH, Fmoc-p-cyano-D-Phe-OH
CAS Number
205526-34-7
Purity
≥ 98% (HPLC)
Molecular Formula
C25H20N2O4
Molecular Weight
412.4
MDL Number
MFCD00672560
PubChem ID
4351133
Melting Point
175-189 °C
Appearance
White product
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Phe(4-CN)-OH, Fmoc-p-cyano-D-Phe-OH
CAS Number
205526-34-7
Purity
≥ 98% (HPLC)
Molecular Formula
C25H20N2O4
Molecular Weight
412.4
MDL Number
MFCD00672560
PubChem ID
4351133
Melting Point
175-189 °C
Appearance
White product
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-cyano-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: Its unique structure enables the incorporation of cyano groups, which can enhance the biological activity of peptide-based drugs, making it valuable in pharmaceutical research.
  • Bioconjugation: The Fmoc protecting group facilitates selective reactions, enabling the attachment of peptides to various biomolecules, which is crucial in developing targeted therapies.
  • Research in Neuroscience: This compound can be used to study neuropeptides, contributing to the understanding of neurological pathways and potential treatments for neurodegenerative diseases.
  • Material Science: Its properties allow for the development of novel materials with specific functionalities, such as drug delivery systems or biosensors, enhancing the scope of applications in material engineering.

Citations