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Catalog Number:
04715
CAS Number:
185379-40-2
Fmoc-3-(2'-pyridyl)-L-alanine
Purity:
≥ 99% (Chiral HPLC)
Synonym(s):
Fmoc-L-Ala(2'-pyridyl)-OH, Fmoc-â-(2'-pyridyl)-Ala-OH, Fmoc-(S)-2-amino-3-(3'-pyridyl)propanoic acid
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$127.79 /1G
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Product Information

Fmoc-3-(2'-pyridyl)-L-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique pyridine moiety enhances its reactivity and solubility, making it an ideal choice for researchers focusing on complex peptide structures.

In practical applications, Fmoc-3-(2'-pyridyl)-L-alanine is particularly valuable in the development of bioactive peptides and pharmaceuticals, where precise control over amino acid sequences is essential. Its ability to facilitate the synthesis of peptides with specific biological activities opens avenues in medicinal chemistry, particularly in the design of targeted therapies and novel drug candidates. Researchers appreciate its compatibility with various coupling reagents and its stability under standard peptide synthesis conditions, making it a reliable choice for both academic and industrial applications.

Synonyms
Fmoc-L-Ala(2'-pyridyl)-OH, Fmoc-â-(2'-pyridyl)-Ala-OH, Fmoc-(S)-2-amino-3-(3'-pyridyl)propanoic acid
CAS Number
185379-40-2
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C23H20N2O4
Molecular Weight
388.4
MDL Number
MFCD00672564
PubChem ID
4600724
Appearance
White powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Ala(2'-pyridyl)-OH, Fmoc-â-(2'-pyridyl)-Ala-OH, Fmoc-(S)-2-amino-3-(3'-pyridyl)propanoic acid
CAS Number
185379-40-2
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C23H20N2O4
Molecular Weight
388.4
MDL Number
MFCD00672564
PubChem ID
4600724
Appearance
White powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-(2'-pyridyl)-L-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its unique structure makes it valuable in the design of bioactive peptides, which can lead to the development of new therapeutic agents targeting various diseases.
  • Bioconjugation: The compound can be used in bioconjugation processes, facilitating the attachment of peptides to proteins or other biomolecules, enhancing their stability and functionality.
  • Research in Neuroscience: Its pyridine moiety is beneficial for studying neuroactive peptides, which can help in understanding neurological pathways and developing treatments for neurodegenerative diseases.
  • Analytical Chemistry: Fmoc-3-(2'-pyridyl)-L-alanine can be employed as a standard in analytical methods, aiding in the quantification of peptides in complex biological samples.

Citations