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Catalog Number:
04978
CAS Number:
142855-80-9
Nα-Z-Nβ-Fmoc-L-2,3-diaminopropionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Z-L-Dap(Fmoc)-OH
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$58.39 /1G
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Product Information

Na-Z-Nb-Fmoc-L-2,3-diaminopropionic acid is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound, characterized by its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, is particularly valuable in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptides with high purity. Its structure not only enhances the stability of the amino acid during synthesis but also facilitates the selective deprotection of the Fmoc group, making it an essential tool for researchers in the fields of medicinal chemistry and biochemistry.

This compound is widely utilized in the development of peptide-based therapeutics, including those targeting various diseases such as cancer and metabolic disorders. Its ability to form stable peptide bonds and its compatibility with various coupling reagents make it an ideal choice for researchers looking to explore new therapeutic avenues. Additionally, Na-Z-Nb-Fmoc-L-2,3-diaminopropionic acid offers advantages over similar compounds due to its enhanced solubility and reactivity, which can lead to improved yields in peptide synthesis. This makes it a preferred option for professionals seeking reliable and efficient solutions in their research and development projects.

Synonyms
Z-L-Dap(Fmoc)-OH
CAS Number
142855-80-9
Purity
≥ 99% (HPLC)
Molecular Formula
C26H24N2O6
Molecular Weight
460.5
MDL Number
MFCD00274016
PubChem ID
4339839
Appearance
White amorphous powder
Optical Rotation
[a]20D = -10 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Z-L-Dap(Fmoc)-OH
CAS Number
142855-80-9
Purity
≥ 99% (HPLC)
Molecular Formula
C26H24N2O6
Molecular Weight
460.5
MDL Number
MFCD00274016
PubChem ID
4339839
Appearance
White amorphous powder
Optical Rotation
[a]20D = -10 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Z-Nb-Fmoc-L-2,3-diaminopropionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in the development of therapeutic proteins. Its unique structure allows for the incorporation of specific amino acid sequences that can enhance biological activity.
  • Drug Development: In pharmaceutical research, it is used to create novel drug candidates. The ability to modify its structure helps in optimizing the pharmacokinetic properties of potential drugs.
  • Bioconjugation: This chemical is valuable in bioconjugation processes, where it can be linked to other biomolecules, such as antibodies or enzymes, to create targeted drug delivery systems, improving treatment efficacy.
  • Research in Neuroscience: It is applied in studies related to neuropeptides, aiding in the understanding of neurological pathways and the development of treatments for neurological disorders.
  • Custom Synthesis: Researchers often utilize it for custom synthesis projects, allowing for the creation of tailored compounds that meet specific research needs, thus providing flexibility in experimental design.

Citations