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Catalog Number:
04992
CAS Number:
136590-09-5
Fmoc-3-nitro-L-tyrosine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-m-nitro-L-Tyr-OH
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Product Information

Fmoc-3-nitro-L-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique nitro group enhances the compound's reactivity, making it an excellent choice for researchers focused on developing novel therapeutic agents. Fmoc-3-nitro-L-tyrosine is particularly valuable in the synthesis of bioactive peptides and can be employed in various applications, including the design of enzyme inhibitors and the study of protein interactions.

Moreover, this compound's stability and compatibility with standard coupling reagents make it a preferred choice for chemists looking to streamline their synthesis processes. Its ability to facilitate the introduction of functional groups into peptides opens up new avenues for research in medicinal chemistry and biochemistry. With its robust profile, Fmoc-3-nitro-L-tyrosine stands out as a key building block for innovative research and development in the pharmaceutical industry.

Synonyms
Fmoc-m-nitro-L-Tyr-OH
CAS Number
136590-09-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20N2O7
Molecular Weight
448.4
MDL Number
MFCD00171383
PubChem ID
3356884
Melting Point
148 - 174 °C (Lit.)
Appearance
Light yellow to yellow owder
Optical Rotation
[a]D20 = 15 ± 4 º
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-m-nitro-L-Tyr-OH
CAS Number
136590-09-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20N2O7
Molecular Weight
448.4
MDL Number
MFCD00171383
PubChem ID
3356884
Melting Point
148 - 174 °C (Lit.)
Appearance
Light yellow to yellow owder
Optical Rotation
[a]D20 = 15 ± 4 º
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-nitro-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of nitro groups that can be used for further modifications.
  • Drug Development: Its unique properties make it valuable in the design of novel pharmaceuticals, especially those targeting specific biological pathways, enhancing the effectiveness of drug candidates.
  • Bioconjugation: The nitro group can be selectively reduced, enabling the attachment of various biomolecules, which is crucial in creating targeted therapies and diagnostic tools in biomedicine.
  • Fluorescent Probes: This compound can be utilized in the development of fluorescent probes for imaging applications, aiding researchers in visualizing cellular processes in real-time.
  • Research in Neuroscience: Its structural similarity to neurotransmitters allows for studies in neurobiology, helping researchers understand receptor interactions and signaling pathways.

Citations