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Catalog Number:
05746
CAS Number:
88743-98-0
Fmoc-Leu-Leu-OH
Purity:
≥ 99% (HPLC)
Documents
$67.60 /1G
Pack Size Availability Price
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Product Information

Fmoc-Leu-Leu-OH is a versatile amino acid derivative widely utilized in peptide synthesis and research applications. This compound, known for its protective Fmoc (9-fluorenylmethoxycarbonyl) group, facilitates the selective coupling of amino acids, making it an essential building block in the production of complex peptides. Its unique structure enhances stability and solubility, allowing for efficient synthesis processes in both academic and industrial settings. Researchers often leverage Fmoc-Leu-Leu-OH in the development of therapeutic peptides, particularly in the fields of drug discovery and development, where precise amino acid sequences are crucial for biological activity.

Additionally, Fmoc-Leu-Leu-OH is recognized for its role in solid-phase peptide synthesis (SPPS), where it contributes to the streamlined assembly of peptides with high purity and yield. Its application extends to the synthesis of cyclic peptides and peptidomimetics, which are vital in the design of novel therapeutics. The compound's favorable properties, such as its ability to enhance the stability of synthesized peptides, make it a preferred choice among researchers and industry professionals seeking reliable and efficient solutions in peptide chemistry.

CAS Number
88743-98-0
Purity
≥ 99% (HPLC)
Molecular Formula
C27H34N2O5
Molecular Weight
466.58
MDL Number
MFCD01632054
PubChem ID
71319952
Melting Point
93 - 103 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -16 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
CAS Number
88743-98-0
Purity
≥ 99% (HPLC)
Molecular Formula
C27H34N2O5
Molecular Weight
466.58
MDL Number
MFCD01632054
PubChem ID
71319952
Melting Point
93 - 103 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -16 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Leu-Leu-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing researchers to create complex peptide sequences efficiently.
  • Drug Development: Its role in the development of peptide-based drugs is significant, as it can enhance the stability and bioavailability of therapeutic peptides, making it valuable in pharmaceutical research.
  • Bioconjugation: Fmoc-Leu-Leu-OH can be used in bioconjugation processes, where it helps in attaching peptides to other biomolecules, facilitating the creation of targeted drug delivery systems.
  • Protein Engineering: Researchers utilize this compound in protein engineering to modify protein structures, aiding in the design of proteins with improved functionalities for various applications.
  • Diagnostics: Its application in developing peptide-based diagnostic tools is noteworthy, as it can be used to create specific assays for disease detection, enhancing the accuracy of medical diagnostics.

Citations