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Catalog Number:
07390
CAS Number:
114873-07-3
Boc-p-trifluoromethyl-L-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Phe(4-CF3)-OH, Boc-L-Phe(4-trifluoromethyl)-OH, Boc-Phe(4-CF3)-OH
Documents
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Product Information

Boc-p-trifluoromethyl-L-phenylalanine is a valuable amino acid derivative known for its unique trifluoromethyl group, which enhances its bioactivity and stability. This compound is widely utilized in the synthesis of peptide-based pharmaceuticals and serves as a crucial building block in medicinal chemistry. Its distinctive properties make it particularly advantageous for researchers focused on developing novel therapeutic agents, as the trifluoromethyl moiety can significantly influence the pharmacokinetics and pharmacodynamics of the resulting compounds.

In addition to its applications in drug discovery, Boc-p-trifluoromethyl-L-phenylalanine is also employed in the study of protein interactions and enzyme activity, providing insights into biological processes. Its ability to modify peptide structures allows for the exploration of new pathways in drug design, making it an essential tool for both academic and industrial researchers. With its combination of stability and reactivity, this compound stands out as a preferred choice for those looking to innovate in the field of peptide synthesis and medicinal chemistry.

Synonyms
Boc-L-Phe(4-CF3)-OH, Boc-L-Phe(4-trifluoromethyl)-OH, Boc-Phe(4-CF3)-OH
CAS Number
114873-07-3
Purity
≥ 99% (HPLC)
Molecular Formula
C15H18F3NO4
Molecular Weight
333.31
MDL Number
MFCD00792407
PubChem ID
2756832
Appearance
Off-white powder
Optical Rotation
[a]20D = 5 ± 0.7 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Phe(4-CF3)-OH, Boc-L-Phe(4-trifluoromethyl)-OH, Boc-Phe(4-CF3)-OH
CAS Number
114873-07-3
Purity
≥ 99% (HPLC)
Molecular Formula
C15H18F3NO4
Molecular Weight
333.31
MDL Number
MFCD00792407
PubChem ID
2756832
Appearance
Off-white powder
Optical Rotation
[a]20D = 5 ± 0.7 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-p-trifluoromethyl-L-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound is a valuable building block in the synthesis of peptides, particularly in the pharmaceutical industry, where it helps create compounds with enhanced biological activity.
  • Drug Development: Its unique trifluoromethyl group can improve the pharmacokinetic properties of drug candidates, making it essential in the design of new therapeutics.
  • Bioconjugation: The compound can be used in bioconjugation strategies to attach drugs to antibodies or other biomolecules, enhancing targeted delivery in cancer therapies.
  • Research in Neuroscience: It serves as a tool in studying neurotransmitter receptors, providing insights into neurological disorders and potential treatments.
  • Material Science: The compound's properties make it useful in developing novel materials, such as polymers with specific functionalities for various applications.

Citations