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Catalog Number:
07547
CAS Number:
90468-17-0
Z-Leu-Leu-Arg-AMC
Temperature Sensitive
Documents
$154.70 /5MG
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Product Information

Z-Leu-Leu-Arg-AMC is a highly specialized peptide substrate that plays a crucial role in biochemical research and drug development. This compound is particularly valued for its application in studying protease activity, especially in the context of cancer research and therapeutic development. Its unique structure allows for the selective cleavage by specific enzymes, making it an essential tool for researchers aiming to understand enzyme kinetics and substrate specificity. The incorporation of the AMC (7-amino-4-methylcoumarin) moiety provides a fluorescent signal upon cleavage, enabling real-time monitoring of enzymatic reactions, which is invaluable in high-throughput screening processes.

In addition to its applications in protease assays, Z-Leu-Leu-Arg-AMC is also utilized in the development of targeted therapies, where understanding the interactions between enzymes and substrates can lead to innovative treatment strategies. Its stability and specificity make it a preferred choice among professionals in biochemistry and molecular biology. Researchers can leverage this compound to gain insights into proteolytic pathways, paving the way for advancements in drug discovery and therapeutic interventions.

CAS Number
90468-17-0
Molecular Formula
C36H49N7O7
Molecular Weight
691.83
MDL Number
MFCD00238474
Conditions
Store at -0°C.
General Information
CAS Number
90468-17-0
Molecular Formula
C36H49N7O7
Molecular Weight
691.83
MDL Number
MFCD00238474
Conditions
Store at -0°C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-Leu-Leu-Arg-AMC is widely utilized in research focused on

  • Protease Activity Assays: This compound serves as a substrate for various proteases, allowing researchers to measure enzyme activity in biological samples, which is crucial for understanding metabolic processes.
  • Drug Development: It plays a role in the screening of potential drug candidates by providing insights into enzyme interactions, helping pharmaceutical companies design more effective therapeutics.
  • Biochemical Research: Used in studies related to protein synthesis and degradation, it aids scientists in exploring cellular mechanisms and the effects of different compounds on protein function.
  • Diagnostics: The compound can be employed in diagnostic assays to detect specific protease-related diseases, offering a valuable tool for clinical laboratories.
  • Biotechnology Applications: In the field of biotechnology, it is utilized in the development of biosensors that detect protease activity, which can be applied in various industrial processes.

Citations