Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
12741
CAS Number:
352523-15-0
Fmoc-D-Phe(2-trifluoromethyl)-OH
Purity:
≥ 99% (HPLC, Chiral purity)
Synonym(s):
Fmoc-D-Phe(2-CF3)-OH, Fmoc-o-trifluoromethyl-D-phenylalanine, (R-Fmoc-2-amino-3-(2-trifluoromethylphenyl)propionicacid
Documents
$65.40 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-D-Phe(2-trifluoromethyl)-OH is a specialized amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorinated phenyl group, which enhances its properties, making it an attractive choice for researchers focused on developing novel therapeutics. The Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of complex peptides with high purity and yield. Its unique trifluoromethyl substitution not only improves lipophilicity but also contributes to the stability of the resulting peptides, making them more effective in biological applications.

In the pharmaceutical industry, Fmoc-D-Phe(2-trifluoromethyl)-OH is particularly valuable in the design of peptide-based drugs, where precision and stability are paramount. Researchers have successfully employed this compound in the synthesis of bioactive peptides, which can serve as potential candidates for treating various diseases, including cancer and metabolic disorders. The compound’s ability to enhance the pharmacokinetic properties of peptides positions it as a key player in advancing peptide therapeutics, making it an essential tool for professionals in medicinal chemistry and drug discovery.

Synonyms
Fmoc-D-Phe(2-CF3)-OH, Fmoc-o-trifluoromethyl-D-phenylalanine, (R-Fmoc-2-amino-3-(2-trifluoromethylphenyl)propionicacid
CAS Number
352523-15-0
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD01863051
PubChem ID
4223809
Appearance
White to off-white solid
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Phe(2-CF3)-OH, Fmoc-o-trifluoromethyl-D-phenylalanine, (R-Fmoc-2-amino-3-(2-trifluoromethylphenyl)propionicacid
CAS Number
352523-15-0
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD01863051
PubChem ID
4223809
Appearance
White to off-white solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-Phe(2-trifluoromethyl)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups. Its stability under various conditions makes it a preferred choice in complex peptide synthesis.
  • Drug Development: The trifluoromethyl group enhances the pharmacological properties of peptides, improving their bioavailability and metabolic stability. This is particularly beneficial in the pharmaceutical industry for developing new therapeutic agents.
  • Bioconjugation: It is used in bioconjugation techniques to attach peptides to other biomolecules, such as antibodies or enzymes, facilitating targeted drug delivery systems in cancer therapy and diagnostics.
  • Material Science: The compound's unique properties allow it to be incorporated into polymeric materials, enhancing their performance in applications like drug delivery systems and biomaterials.
  • Research and Development: In academic and industrial laboratories, it is a valuable tool for researchers exploring new peptide-based therapies, providing a versatile platform for experimentation and innovation.

Citations