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Catalog Number:
12775
CAS Number:
700377-76-0
Fmoc-Nω-(2,2,5,7,8-pentamethyl-chromane-6-sulfonyl)-L-β-homoarginine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-HomoArg(Pmc)-OH
Documents
$93.14 /25MG
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Product Information

Fmoc-Nw-(2,2,5,7,8-pentamethyl-chromane-6-sulfonyl)-L-b-homoarginine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its unique sulfonyl group, which enhances solubility and stability in various biological environments. Researchers and industry professionals utilize this compound in the design of peptide-based therapeutics and in the development of novel biomaterials. Its distinctive structure allows for improved binding interactions and bioactivity, making it an excellent choice for applications in medicinal chemistry and biochemistry.

The versatility of Fmoc-Nw-(2,2,5,7,8-pentamethyl-chromane-6-sulfonyl)-L-b-homoarginine extends to its use in solid-phase peptide synthesis, where it serves as a protective group that can be easily removed under mild conditions. This feature streamlines the synthesis process, allowing for the efficient production of complex peptides. Additionally, its potential in enhancing the pharmacokinetic properties of peptide drugs positions it as a valuable asset in pharmaceutical research and development.

Synonyms
Fmoc-L-β-HomoArg(Pmc)-OH
CAS Number
700377-76-0
Purity
≥ 98% (HPLC)
Molecular Formula
C36H44N4O7S
Molecular Weight
676.84
MDL Number
MFCD03788172
PubChem ID
53398093
Appearance
White solid
Optical Rotation
[a]D25 = -5.5 ± 1.5º (C=1, in CHCl3)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-β-HomoArg(Pmc)-OH
CAS Number
700377-76-0
Purity
≥ 98% (HPLC)
Molecular Formula
C36H44N4O7S
Molecular Weight
676.84
MDL Number
MFCD03788172
PubChem ID
53398093
Appearance
White solid
Optical Rotation
[a]D25 = -5.5 ± 1.5º (C=1, in CHCl3)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Nw-(2,2,5,7,8-pentamethyl-chromane-6-sulfonyl)-L-b-homoarginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in peptide synthesis, allowing for the selective modification of amino acids without affecting others, which is crucial for creating complex peptides.
  • Drug Development: It plays a role in the design of novel therapeutic agents, particularly in targeting specific biological pathways, enhancing drug efficacy and specificity.
  • Bioconjugation: The sulfonyl group facilitates bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in developing biosensors and targeted drug delivery systems.
  • Research in Cancer Therapeutics: Its unique structure allows researchers to explore new avenues in cancer treatment by modifying peptides to improve their interaction with cancer cells.
  • Protein Engineering: This compound is valuable in protein engineering, where it helps in the design of proteins with enhanced stability and activity, addressing challenges in biopharmaceutical production.

Citations