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Catalog Number:
12844
CAS Number:
401933-16-2
Fmoc-2-cyano-L-phenylalanine
Purity:
≥ 98% (ee)
Synonym(s):
Fmoc-L-Phe(2-CN)-OH, Fmoc-o-Cyano-L-Phe-OH, Fmoc-Phe(2-CN)-OH
Documents
$93.14 /250MG
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Product Information

Fmoc-2-cyano-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block for researchers in the field of medicinal chemistry. Its unique structure, characterized by the presence of a cyano group, enhances its reactivity and provides opportunities for further functionalization, which can be advantageous in the design of novel therapeutic agents.

In practical applications, Fmoc-2-cyano-L-phenylalanine has been employed in the synthesis of bioactive peptides, contributing to advancements in targeted drug delivery systems and the development of peptide-based therapeutics. Its ability to facilitate the incorporation of non-standard amino acids into peptide chains opens new avenues for research in protein engineering and the creation of peptide libraries for high-throughput screening. Researchers and industry professionals will find this compound invaluable for its efficiency and effectiveness in peptide synthesis, paving the way for innovative solutions in pharmaceutical development.

Synonyms
Fmoc-L-Phe(2-CN)-OH, Fmoc-o-Cyano-L-Phe-OH, Fmoc-Phe(2-CN)-OH
CAS Number
401933-16-2
Purity
≥ 98% (ee)
Molecular Formula
C25H20N2O4
Molecular Weight
412.4
MDL Number
MFCD01863771
PubChem ID
3382520
Appearance
White powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Phe(2-CN)-OH, Fmoc-o-Cyano-L-Phe-OH, Fmoc-Phe(2-CN)-OH
CAS Number
401933-16-2
Purity
≥ 98% (ee)
Molecular Formula
C25H20N2O4
Molecular Weight
412.4
MDL Number
MFCD01863771
PubChem ID
3382520
Appearance
White powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-2-cyano-L-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for various applications in drug discovery and development.
  • Bioconjugation: Its unique functional groups facilitate bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in developing targeted therapies and diagnostics.
  • Fluorescent Probes: The chemical can be incorporated into fluorescent probes, enhancing the ability to visualize biological processes in live cells, which is crucial for cellular and molecular biology studies.
  • Drug Design: Researchers utilize this compound in structure-activity relationship studies, helping to optimize the efficacy and selectivity of new pharmaceutical candidates.
  • Material Science: Its properties allow for the development of advanced materials, including hydrogels and nanomaterials, which have applications in drug delivery systems and tissue engineering.

Citations