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Catalog Number:
12858
CAS Number:
216312-53-7
Boc-2-cyano-L-phenylalanine
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
Boc-L-Phe(2-CN)-OH, Boc-o-Cyano-L-Phe-OH, (S-Boc-2-amino-(2-cyanophenyl)propanoic acid
Documents
$95.00 /250MG
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Product Information

Boc-2-cyano-L-phenylalanine is a versatile amino acid derivative that plays a significant role in peptide synthesis and drug development. This compound is particularly valued for its ability to introduce cyano groups into peptides, which can enhance biological activity and stability. Its unique structure allows for the incorporation of the Boc (tert-butyloxycarbonyl) protecting group, making it an excellent choice for researchers looking to streamline the synthesis of complex peptides. The cyano group can serve as a handle for further chemical modifications, enabling the development of novel therapeutic agents.

In the pharmaceutical industry, Boc-2-cyano-L-phenylalanine is utilized in the design of inhibitors and other bioactive compounds. Its application extends to the fields of medicinal chemistry and biochemistry, where it aids in the exploration of new drug candidates. Researchers appreciate its compatibility with various coupling reactions, which facilitates efficient peptide assembly. With its favorable properties and practical applications, Boc-2-cyano-L-phenylalanine stands out as a valuable tool for advancing peptide-based research and development.

Synonyms
Boc-L-Phe(2-CN)-OH, Boc-o-Cyano-L-Phe-OH, (S-Boc-2-amino-(2-cyanophenyl)propanoic acid
CAS Number
216312-53-7
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C15H18N2O4
Molecular Weight
290.3
MDL Number
MFCD01860623
PubChem ID
4393344
Melting Point
90 - 97 °C
Appearance
White powder
Optical Rotation
[a]D25 = -33 ± 2 º (C=1% in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Phe(2-CN)-OH, Boc-o-Cyano-L-Phe-OH, (S-Boc-2-amino-(2-cyanophenyl)propanoic acid
CAS Number
216312-53-7
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C15H18N2O4
Molecular Weight
290.3
MDL Number
MFCD01860623
PubChem ID
4393344
Melting Point
90 - 97 °C
Appearance
White powder
Optical Rotation
[a]D25 = -33 ± 2 º (C=1% in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-2-cyano-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of novel therapeutic agents. Its unique structure allows for the incorporation of cyano groups, enhancing the properties of the resulting peptides.
  • Drug Development: It plays a significant role in the pharmaceutical industry for designing inhibitors and modulators of biological pathways, particularly in cancer research, where specific amino acid modifications can improve drug efficacy.
  • Bioconjugation: The compound is used in bioconjugation processes to attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems and diagnostic tools.
  • Research in Neuroscience: Its derivatives are explored in neuroscience for studying neurotransmitter systems, providing insights into the mechanisms of action of various neuroactive compounds.
  • Analytical Chemistry: Boc-2-cyano-L-phenylalanine is utilized in analytical methods to quantify amino acids in complex mixtures, aiding in quality control and research applications in food and pharmaceutical industries.

Citations