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Catalog Number:
14497
CAS Number:
1007840-62-1
Fmoc-S-trityl-D-homocysteine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-D-Homocys(Trt)-OH, (R-2-(Fmoc-amino)-4-tritylsulfanyl-butyric acid
Documents
$70.00 /100MG
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Product Information

Fmoc-S-trityl-D-homocysteine is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which facilitates the selective deprotection of amino acids during the synthesis process, making it an essential tool for chemists in the field of medicinal chemistry. Its unique trityl (triphenylmethyl) group enhances stability and solubility, allowing for efficient handling and manipulation in various chemical reactions.

Researchers and industry professionals can leverage Fmoc-S-trityl-D-homocysteine in the development of peptide-based therapeutics, particularly in the design of inhibitors and modulators targeting specific biological pathways. Its application extends to the synthesis of cyclic peptides and other complex structures, providing a robust framework for innovative drug discovery. With its favorable properties and functional versatility, this compound stands out as a preferred choice for those engaged in advanced peptide chemistry.

Synonyms
Fmoc-D-Homocys(Trt)-OH, (R-2-(Fmoc-amino)-4-tritylsulfanyl-butyric acid
CAS Number
1007840-62-1
Purity
≥ 97% (HPLC)
Molecular Formula
C38H33NO4S
Molecular Weight
599.74
MDL Number
MFCD05663440
PubChem ID
53395531
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +17 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Homocys(Trt)-OH, (R-2-(Fmoc-amino)-4-tritylsulfanyl-butyric acid
CAS Number
1007840-62-1
Purity
≥ 97% (HPLC)
Molecular Formula
C38H33NO4S
Molecular Weight
599.74
MDL Number
MFCD05663440
PubChem ID
53395531
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +17 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-trityl-D-homocysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others, which is crucial in developing complex biomolecules.
  • Drug Development: It plays a significant role in the pharmaceutical industry for creating novel therapeutic agents, particularly in designing peptide-based drugs that target specific diseases.
  • Bioconjugation: Researchers use it to facilitate the attachment of biomolecules to surfaces or other molecules, enhancing the effectiveness of drug delivery systems and diagnostic tools.
  • Protein Engineering: This compound aids in the modification of proteins, enabling scientists to study protein interactions and functions, which is vital in understanding biological processes.
  • Analytical Chemistry: It is employed in various analytical techniques to improve the resolution and sensitivity of assays, making it easier to detect and quantify biomolecules in complex samples.

Citations