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Catalog Number:
15089
CAS Number:
1217619-78-7
(R)-3-Fmoc-amino-5-(carboxylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
Purity:
≥ 97% (HPLC)
Documents
$86.23 /25MG
Pack Size Availability Price
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Product Information

(R)-3-Fmoc-amino-5-(carboxylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique benzothiazepine structure, which enhances its potential as a building block for bioactive molecules. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection during peptide synthesis, making it an invaluable tool for researchers in the field of drug development.

The carboxymethyl group further contributes to its reactivity, enabling the formation of various derivatives that can be tailored for specific biological activities. This compound is particularly relevant in the development of pharmaceuticals targeting neurological disorders and cancer, where benzothiazepine derivatives have shown promising results. Its ability to facilitate complex synthesis while maintaining stability under various conditions makes it a preferred choice among professionals in medicinal chemistry and biochemistry.

CAS Number
1217619-78-7
Purity
≥ 97% (HPLC)
Molecular Formula
C26H22N2O5S
Molecular Weight
474.53
MDL Number
MFCD04112698
PubChem ID
4712609
Appearance
White powder
Optical Rotation
[a]D20 = -190 to -205º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
CAS Number
1217619-78-7
Purity
≥ 97% (HPLC)
Molecular Formula
C26H22N2O5S
Molecular Weight
474.53
MDL Number
MFCD04112698
PubChem ID
4712609
Appearance
White powder
Optical Rotation
[a]D20 = -190 to -205º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-3-Fmoc-amino-5-(carboxylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of desired products.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing novel therapeutic agents, especially those targeting specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial for creating targeted drug delivery systems.
  • Research in Neuroscience: Its unique structure makes it valuable for studying receptor interactions and signaling pathways, contributing to advancements in understanding neurological disorders.
  • Analytical Chemistry: This chemical is employed in various analytical techniques, including chromatography, to separate and identify complex mixtures, aiding in quality control and research analysis.

Citations